U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 15:15:12 GMT 2023
Edited
by admin
on Sat Dec 16 15:15:12 GMT 2023
Source Materials Class ORGANISM
Source Materials Type AUTOLOGOUS HUMAN
Source Materials State LIVE GENETICALLY MODIFIED
Source Materials Parent
Part BLOOD
Fraction Material Type CELLS
Fraction Name T-CELL
Record UNII
W86XKJ6C6Y
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TEBROCABTAGENE AUTOLEUCEL
INN  
Official Name English
AUTOLOGOUS T CELLS, TRANSDUCED WITH A REPLICATION INCOMPETENT MOLONEY MURINE LEUKEMIA VIRUS (MOMLV) (A RETROVIRUS) VECTOR THAT ENCODES A CHIMERIC ANTIGEN RECEPTOR (CAR) TARGETING HUMAN B-LYMPHOCYTE ANTIGEN CD19 (CD19 MOLECULE, B-LYMPHOCYTE SURFACE ANTIGE
Common Name English
tebrocabtagene autoleucel [INN]
Common Name English
Code System Code Type Description
INN
11110
Created by admin on Sat Dec 16 15:15:12 GMT 2023 , Edited by admin on Sat Dec 16 15:15:12 GMT 2023
PRIMARY
FDA UNII
W86XKJ6C6Y
Created by admin on Sat Dec 16 15:15:12 GMT 2023 , Edited by admin on Sat Dec 16 15:15:12 GMT 2023
PRIMARY
NCI_THESAURUS
C174931
Created by admin on Sat Dec 16 15:15:12 GMT 2023 , Edited by admin on Sat Dec 16 15:15:12 GMT 2023
PRIMARY
Related Record Type Details
TARGET->LIGAND
Related Record Type Details
ACTIVE MOIETY

Agent Modifications

Modification Process Modification Role Modification Type Amount Fragment Name Fragment ID
RETROVIRAL TRANSFECTION MOLONEY MURINE LEUKEMIA VIRUS (MOMLV) (A RETROVIRUS) VECTOR ENCODES A CHIMERIC ANTIGEN RECEPTOR (CAR) TARGETING HUMAN B-LYMPHOCYTE ANTIGEN CD19 1T4Q3KIT5R

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
GENE_EXPRESSION VECTOR TEBROCABTAGENE AUTOLEUCEL VECTOR DM4ANZ9B4N