Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H7N5 |
| Molecular Weight | 149.1533 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CNC1=NC=NC2=C1N=CN2
InChI
InChIKey=CKOMXBHMKXXTNW-UHFFFAOYSA-N
InChI=1S/C6H7N5/c1-7-5-4-6(10-2-8-4)11-3-9-5/h2-3H,1H3,(H2,7,8,9,10,11)
| Molecular Formula | C6H7N5 |
| Molecular Weight | 149.1533 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Conflicts targeting epigenetic systems and their resolution by cell death: novel concepts for methyl-specific and other restriction systems. | 2010-12 |
|
| Riboswitches as hormone receptors: hypothetical cytokinin-binding riboswitches in Arabidopsis thaliana. | 2010-10-20 |
|
| Genomic N(6)-methyladenine determination by MEKC with LIF. | 2010-10 |
|
| Discrimination of N6-methyl adenine in a specific DNA sequence. | 2010-08-14 |
|
| Cloning of NruI and Sbo13I restriction and modification sstems in E. coli and amino acid sequence comparison of M.NruI and M.Sbo13I with other amino-methyltransferases. | 2010-05-24 |
|
| Biosynthesis and molecular genetics of polyketides in marine dinoflagellates. | 2010-03-31 |
|
| Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds. | 2010-02-19 |
|
| Insensitivity of chloroplast gene expression to DNA methylation. | 2009-07 |
|
| Effect of 1-methyladenine on thermodynamic stabilities of double-helical DNA structures. | 2009-05-06 |
|
| Roles of DNA adenine methylation in host-pathogen interactions: mismatch repair, transcriptional regulation, and more. | 2009-05 |
|
| M1.MboII and M2.MboII type IIS methyltransferases: different specificities, the same target. | 2009-04 |
|
| Expansion of a chromosomal repeat in Escherichia coli: roles of replication, repair, and recombination functions. | 2009-02-23 |
|
| H1 histone modulates DNA hydrolysis with WEN1 and WEN2 endonucleases from wheat coleoptiles. | 2009-02 |
|
| Separation of purine and pyrimidine bases by ion chromatography with direct conductivity detection. | 2008-06-06 |
|
| Clocks and switches: bacterial gene regulation by DNA adenine methylation. | 2008-04 |
|
| Cell death upon epigenetic genome methylation: a novel function of methyl-specific deoxyribonucleases. | 2008 |
|
| Anion-pi interactions in bisadenine derivatives: a combined crystallographic and theoretical study. | 2007-12-10 |
|
| A view of an elemental naturalist at the DNA world (base composition, sequences, methylation). | 2007-12 |
|
| Mapping sequences by parts. | 2007-09-19 |
|
| Growth of the protozoan parasite Entamoeba histolytica in 5-azacytidine has limited effects on parasite gene expression. | 2007-01-05 |
|
| [DNA methylation and epigenetics]. | 2006-09 |
|
| Calcium-stimulated guanosine--inosine nucleosidase from yellow lupin (Lupinus luteus). | 2006-07 |
|
| Undetectable levels of N6-methyl adenine in mouse DNA: Cloning and analysis of PRED28, a gene coding for a putative mammalian DNA adenine methyltransferase. | 2006-05-29 |
|
| N6-methyl-adenine: an epigenetic signal for DNA-protein interactions. | 2006-03 |
|
| N6-methyladenine: the other methylated base of DNA. | 2006-03 |
|
| DNA methylation in plants. | 2006 |
|
| DNA methylation impacts the cleavage activity of Chlorella virus topoisomerase II. | 2005-11-22 |
|
| Location of the bases modified by M.BcoKIA and M.BcoKIB methylases in the sequence 5 -CTCTTC-3 /5 -GAAGAG-3. | 2005-10 |
|
| Effect of methylated adenine in plasmid DNA on transgene expression in mice. | 2005-10 |
|
| Deinococcus radiodurans strain R1 contains N6-methyladenine in its genome. | 2005-09-23 |
|
| MnlI--The member of H-N-H subtype of Type IIS restriction endonucleases. | 2005-08-10 |
|
| The language of methylation in genomics of eukaryotes. | 2005-05 |
|
| DNA-[adenine] methylation in lower eukaryotes. | 2005-05 |
|
| Enzymatic DNA methylation is an epigenetic control for genetic functions of the cell. | 2005-05 |
|
| Evidence for the functional expression and pharmacological characterization of adenine receptors in native cells and tissues. | 2005-03 |
|
| Cytokine induction by a bacterial DNA-specific modified base. | 2005-01-28 |
|
| The N6-methyl group of adenine further increases the BI stability of DNA compared to C5-methyl groups. | 2005-01-13 |
|
| GATC-specific restriction and modification systems in treponemes. | 2004 |
|
| Characterization of the LlaCI methyltransferase from Lactococcus lactis subsp. cremoris W15 provides new insights into the biology of type II restriction-modification systems. | 2003-11 |
|
| Influence of local duplex stability and N6-methyladenine on uracil recognition by mismatch-specific uracil-DNA glycosylase (Mug). | 2002-12 |
|
| Synthesis and biological evaluation of novel thioapio dideoxynucleosides. | 2002-05 |
|
| Sequence permutations in the molecular evolution of DNA methyltransferases. | 2002-03-12 |
|
| Characterization of AloI, a restriction-modification system of a new type. | 2001-11-23 |
|
| Identification of a PD-(D/E)XK-like domain with a novel configuration of the endonuclease active site in the methyl-directed restriction enzyme Mrr and its homologs. | 2001-04-18 |
|
| mRNA:guanine-N7 cap methyltransferases: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationships. | 2001 |
|
| Adenine-induced selective apoptosis toward HIV chronically infected cells in vitro. | 2000-07-14 |
|
| Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyl-transferase from Toxoplasma gondii. | 1995-11-09 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:43:00 GMT 2025
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on
Mon Mar 31 18:43:00 GMT 2025
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| Record UNII |
W7IBY2BGAX
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| Record Status |
Validated (UNII)
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| Record Version |
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