MOTRETINIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C23H31NO2
Molecular Weight	353.4977
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	4
Charge	0

SHOW SMILES / InChI

Structure of MOTRETINIDE

Structure Search

SMILES

CCNC(=O)\C=C(C)\C=C\C=C(C)\C=C\C1=C(C)C(C)=C(OC)C=C1C

InChI

InChIKey=IYIYMCASGKQOCZ-DJRRULDNSA-N

InChI=1S/C23H31NO2/c1-8-24-23(25)14-17(3)11-9-10-16(2)12-13-21-18(4)15-22(26-7)20(6)19(21)5/h9-15H,8H2,1-7H3,(H,24,25)/b11-9+,13-12+,16-10+,17-14+

HIDE SMILES / InChI

Molecular Formula	C23H31NO2
Molecular Weight	353.4977
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	4
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/11586072 | https://www.drugs.com/international/motretinide.html

MOTRETINIDE is a retinoic acid derivative. It is used as a topical agent in the treatment of mild to moderate acne.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Ro 11-1430, a new retinoic acid derivative for the topical treatment of acne.	1981	6454596
Motretinide versus benzoyl peroxide in the treatment of acne vulgaris.	1984	6233188
Retinoids--which dermatological indications will benefit in the near future?	2001 Sep-Oct	11586072

Patents

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:16:50 UTC 2023` Edited by `admin` on `Fri Dec 15 15:16:50 UTC 2023`
Record UNII	W786807KL1
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MOTRETINIDE

Official Name

English

RO 11-1430

Code

English

all-trans-N-Ethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenamide

Common Name

English

MOTRETINIDE [USAN]

Common Name

English

MOTRETINIDE [MART.]

Common Name

English

Motretinide [WHO-DD]

Common Name

English

RO-11-1430

Code

English

motretinide [INN]

Common Name

English

NSC-351523

Code

English

MOTRETINIDE [MI]

Common Name

English

TASMADERM

Brand Name

English

2,4,6,8-NONATETRAENAMIDE, N-ETHYL-9-(4-METHOXY-2,3,6-TRIMETHYLPHENYL)-3,7-DIMETHYL-, (ALL-E)-

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C804

Created by admin on Fri Dec 15 15:16:50 UTC 2023 , Edited by admin on Fri Dec 15 15:16:50 UTC 2023

WHO-ATC

D10AD05

Created by admin on Fri Dec 15 15:16:50 UTC 2023 , Edited by admin on Fri Dec 15 15:16:50 UTC 2023

WHO-VATC

QD10AD05

Created by admin on Fri Dec 15 15:16:50 UTC 2023 , Edited by admin on Fri Dec 15 15:16:50 UTC 2023

Code System Code Type Description

NCI_THESAURUS

C90940

Created by admin on Fri Dec 15 15:16:50 UTC 2023 , Edited by admin on Fri Dec 15 15:16:50 UTC 2023

PRIMARY

CAS

56281-36-8

Created by admin on Fri Dec 15 15:16:50 UTC 2023 , Edited by admin on Fri Dec 15 15:16:50 UTC 2023

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DRUG CENTRAL

1849

Created by admin on Fri Dec 15 15:16:50 UTC 2023 , Edited by admin on Fri Dec 15 15:16:50 UTC 2023

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DRUG BANK

DB13368

Created by admin on Fri Dec 15 15:16:50 UTC 2023 , Edited by admin on Fri Dec 15 15:16:50 UTC 2023

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NSC

351523

Created by admin on Fri Dec 15 15:16:50 UTC 2023 , Edited by admin on Fri Dec 15 15:16:50 UTC 2023

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PUBCHEM

6314185

Created by admin on Fri Dec 15 15:16:50 UTC 2023 , Edited by admin on Fri Dec 15 15:16:50 UTC 2023

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FDA UNII

W786807KL1

Created by admin on Fri Dec 15 15:16:50 UTC 2023 , Edited by admin on Fri Dec 15 15:16:50 UTC 2023

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MERCK INDEX

m7640

Created by admin on Fri Dec 15 15:16:50 UTC 2023 , Edited by admin on Fri Dec 15 15:16:50 UTC 2023

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Merck Index

SMS_ID

100000080394

Created by admin on Fri Dec 15 15:16:50 UTC 2023 , Edited by admin on Fri Dec 15 15:16:50 UTC 2023

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WIKIPEDIA

MOTRETINIDE

Created by admin on Fri Dec 15 15:16:50 UTC 2023 , Edited by admin on Fri Dec 15 15:16:50 UTC 2023

PRIMARY

ChEMBL

CHEMBL519260

Created by admin on Fri Dec 15 15:16:50 UTC 2023 , Edited by admin on Fri Dec 15 15:16:50 UTC 2023

PRIMARY

EVMPD

SUB09077MIG

Created by admin on Fri Dec 15 15:16:50 UTC 2023 , Edited by admin on Fri Dec 15 15:16:50 UTC 2023

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INN

4233

Created by admin on Fri Dec 15 15:16:50 UTC 2023 , Edited by admin on Fri Dec 15 15:16:50 UTC 2023

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ECHA (EC/EINECS)

260-094-6

Created by admin on Fri Dec 15 15:16:50 UTC 2023 , Edited by admin on Fri Dec 15 15:16:50 UTC 2023

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EPA CompTox

DTXSID30878633

Created by admin on Fri Dec 15 15:16:50 UTC 2023 , Edited by admin on Fri Dec 15 15:16:50 UTC 2023

PRIMARY

Related Record Type Details


					W786807KL1

ACTIVE MOIETY