2'-O-METHYLGUANOSINE

CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=NC3=C2N=C(N)NC3=O

InChIKey=OVYNGSFVYRPRCG-KQYNXXCUSA-N

InChI=1S/C11H15N5O5/c1-20-7-6(18)4(2-17)21-10(7)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,7-,10-/m1/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

PubMed

Title	Date	PubMed
Anticodon domain methylated nucleosides of yeast tRNA(Phe) are significant recognition determinants in the binding of a phage display selected peptide.	2001 Nov 27	11714272
Identification and characterization of tRNA (Gm18) methyltransferase from Thermus thermophilus HB8: domain structure and conserved amino acid sequence motifs.	2002 Mar	11918670
Inhibition of human immunodeficiency virus 1 replication in vitro by a self-stabilized oligonucleotide with 2'-O-methyl-guanosine-uridine quadruplex motifs.	2003 Apr	12654739
Novel synthesis of 2'-O-methylguanosine.	2003 May 19	12729629
MDPSCL2: a new protecting group for chemoselective synthesis of 2'-O-alkylated guanosines.	2003 May-Aug	14565233
Structure-activity relationship of purine ribonucleosides for inhibition of hepatitis C virus RNA-dependent RNA polymerase.	2004 Apr 22	15084127
An efficient process for synthesis of 2'-O-methyl and 3'-O-methyl guanosine from 2-aminoadenosine using diazomethane and the catalyst stannous chloride.	2006 Mar	16629123
Facile and efficient approach for the synthesis of N(2)-dimethylaminomethylene-2'-O-methylguanosine.	2010 Jan 1	19945873

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:41:47 GMT 2023` Edited by `admin` on `Fri Dec 15 18:41:47 GMT 2023`
Record UNII	W722H4PA1S
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

2'-O-METHYLGUANOSINE

Systematic Name

English

GUANOSINE, 2'-O-METHYL-

Systematic Name

English

Code System Code Type Description

MESH

C024900