Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C33H35FN2O5 |
| Molecular Weight | 558.6398 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@H](O)CC(O)=O)C3=CC=C(F)C=C3)C4=CC=CC=C4
InChI
InChIKey=XUKUURHRXDUEBC-SXOMAYOGSA-N
InChI=1S/C33H35FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/t26-,27+/m1/s1
| Molecular Formula | C33H35FN2O5 |
| Molecular Weight | 558.6398 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
(3S,5R)-atorvastatin is a stereoisomer of atorvastatin. Atorvastatin is a synthetic hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. 3R,5R enantiopure form of atorvastatin (Lipitor, Pfizer; since Nov 2011 generic) is used clinically. It reduces levels of total cholesterol, low-density lipoprotein (LDL)-cholesterol, triglyceride and very low-density lipoprotein (VLDL)-cholesterol and increases high-density lipoprotein (HDL)-cholesterol in patients with a wide variety of dyslipidaemias.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 05:42:27 GMT 2023
by
admin
on
Sat Dec 16 05:42:27 GMT 2023
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| Record UNII |
W6MO59C0CE
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| Record Status |
Validated (UNII)
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| Record Version |
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6093359
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887324-52-9
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DTXSID80237276
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W6MO59C0CE
Created by
admin on Sat Dec 16 05:42:27 GMT 2023 , Edited by admin on Sat Dec 16 05:42:27 GMT 2023
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| Related Record | Type | Details | ||
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
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