GILORALIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 03:51:57 GMT 2025` Edited by `admin` on `Wed Apr 02 03:51:57 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	W6C58X3BFH
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

giloralimab [INN]

Preferred Name

English

GILORALIMAB

Official Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN CD40 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL PR-1614645 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL PR-1614645 .KAPPA.-CHAIN, DIMER

Systematic Name

English

ABBV-927

Code

English

AGONISTIC ANTI-CD40 MONOCLONAL ANTIBODY ABBV-927

Common Name

English

PR-1614645

Code

English

Giloralimab [WHO-DD]

Common Name

English

ANTI-CD40 AGONIST MONOCLONAL ANTIBODY ABBV-927

Common Name

English

Code System Code Type Description

SMS_ID

300000023638

Created by admin on Wed Apr 02 03:51:57 GMT 2025 , Edited by admin on Wed Apr 02 03:51:57 GMT 2025

PRIMARY

INN

11241

Created by admin on Wed Apr 02 03:51:57 GMT 2025 , Edited by admin on Wed Apr 02 03:51:57 GMT 2025

PRIMARY

NCI_THESAURUS

C139553

Created by admin on Wed Apr 02 03:51:57 GMT 2025 , Edited by admin on Wed Apr 02 03:51:57 GMT 2025

PRIMARY

CAS

2226292-20-0

Created by admin on Wed Apr 02 03:51:57 GMT 2025 , Edited by admin on Wed Apr 02 03:51:57 GMT 2025

PRIMARY

FDA UNII

W6C58X3BFH

Created by admin on Wed Apr 02 03:51:57 GMT 2025 , Edited by admin on Wed Apr 02 03:51:57 GMT 2025

PRIMARY

From	To
1_22	1_96
1_139	1_195
1_215	3_219
1_221	2_221
1_224	2_224
1_256	1_316
1_362	1_420
2_22	2_96
2_139	2_195
2_215	4_219
2_256	2_316
2_362	2_420
3_23	3_93
3_139	3_199
4_23	4_93
4_139	4_199

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_292
N	2_292

Related Record Type Details


					CA9PO31PIJ

TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5

TARGET -> AGONIST

Related Record Type Details


					W6C58X3BFH

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_442] [2_442]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL