URABRELIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 20:45:59 GMT 2025` Edited by `admin` on `Tue Apr 01 20:45:59 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	W6284A5K8N
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

URABRELIMAB

Official Name

English

urabrelimab [INN]

Preferred Name

English

SRF-231

Code

English

IMMUNOGLOBULIN IGG4, ANTI-(HUMAN CD47) (HUMAN MONOCLONAL SRF231 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL SRF231 .KAPPA.-CHAIN, DIMER

Systematic Name

English

Urabrelimab [WHO-DD]

Common Name

English

SRF231

Code

English

Classification Tree Code System Code

FDA ORPHAN DRUG

643718

Created by admin on Tue Apr 01 20:45:59 GMT 2025 , Edited by admin on Tue Apr 01 20:45:59 GMT 2025

Code System Code Type Description

SMS_ID

300000024175

Created by admin on Tue Apr 01 20:45:59 GMT 2025 , Edited by admin on Tue Apr 01 20:45:59 GMT 2025

PRIMARY

NCI_THESAURUS

C155976

Created by admin on Tue Apr 01 20:45:59 GMT 2025 , Edited by admin on Tue Apr 01 20:45:59 GMT 2025

PRIMARY

INN

11236

Created by admin on Tue Apr 01 20:45:59 GMT 2025 , Edited by admin on Tue Apr 01 20:45:59 GMT 2025

PRIMARY

CAS

2249722-58-3

Created by admin on Tue Apr 01 20:45:59 GMT 2025 , Edited by admin on Tue Apr 01 20:45:59 GMT 2025

PRIMARY

FDA UNII

W6284A5K8N

Created by admin on Tue Apr 01 20:45:59 GMT 2025 , Edited by admin on Tue Apr 01 20:45:59 GMT 2025

PRIMARY

From	To
1_22	1_96
1_139	2_212
1_152	1_208
1_231	3_231
1_234	3_234
1_266	1_326
1_372	1_430
2_23	2_88
2_132	2_192
3_22	3_96
3_139	4_212
3_152	3_208
3_266	3_326
3_372	3_430
4_23	4_88
4_132	4_192

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_302
N	3_302

Related Record Type Details


					90DHW5TM9S

LEUKOCYTE SURFACE ANTIGEN CD47

TARGET -> INHIBITOR

Related Record Type Details


					W6284A5K8N

ACTIVE MOIETY

Comments:

CD47 Monoclonal Antibody SRF231 Is a Potent Inducer of Macrophage-Mediated Tumor Cell Phagocytosis

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL