PURINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H4N4
Molecular Weight	120.1121
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

N1C=NC2=C1C=NC=N2

InChI

InChIKey=KDCGOANMDULRCW-UHFFFAOYSA-N

InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)

HIDE SMILES / InChI

Molecular Formula	C5H4N4
Molecular Weight	120.1121
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Adenine-induced selective apoptosis toward HIV chronically infected cells in vitro.	2000 Jul 14	10891366
Genome-wide analysis of protein-DNA interactions in living cells.	2001	11305945
Properties of native P2X receptors in rat trigeminal mesencephalic nucleus neurones: lack of correlation with known, heterologously expressed P2X receptors.	2001	11077075
Functional characterization of a maize purine transporter by expression in Aspergillus nidulans.	2001 Apr	11283348
A fluorescent sensor of the phosphorylation state of nucleoside diphosphate kinase and its use to monitor nucleoside diphosphate concentrations in real time.	2001 Apr 24	11305926
Pdx-1 is required for activation in vivo from a duodenum-specific enhancer.	2001 Apr 27	11278481
Inhibition of peroxynitrite-induced dityrosine formation with oxidized and reduced thiols, nitric oxide donors, and purine derivatives.	2001 Feb	11291595
Regulation of hisHF transcription of Aspergillus nidulans by adenine and amino acid limitation.	2001 Feb	11277623
Uric acid mediates photodynamic inactivation of caprine alpha-2-macroglobulin.	2001 Feb	11264889
Characterization of DNA damage at purine residues in oligonucleotides and calf thymus DNA induced by the mutagen 1-nitrosoindole-3-acetonitrile.	2001 Feb	11258964
Interstitial brain adenosine and xanthine increase during jugular venous oxygen desaturations in humans after traumatic brain injury.	2001 Feb	11246323
Interactions between 2-fluoroadenine 9-beta-D-arabinofuranoside and the kinase inhibitor UCN-01 in human leukemia and lymphoma cells.	2001 Feb	11234887
[Pharmacological profiles of mycophenolate mofetil (CellCept), a new immunosuppressive agent].	2001 Feb	11233304
Effect of furosemide on renal excretion of oxypurinol and purine bases.	2001 Feb	11229436
A novel assay for determination of diadenosine polyphosphates in human platelets: studies in normotensive subjects and in patients with essential hypertension.	2001 Feb	11212966
The folate cycle and disease in humans.	2001 Feb	11169015
The evolution of ribonucleotide reduction revisited.	2001 Feb	11166566
A novel proton-dependent nucleoside transporter, CeCNT3, from Caenorhabditis elegans.	2001 Feb	11160871
Analysis of purine- and pyrimidine-induced vascular responses in the isolated rat cerebral arteriole.	2001 Feb	11158976
Melphalan and purine analog-containing preparative regimens: reduced-intensity conditioning for patients with hematologic malignancies undergoing allogeneic progenitor cell transplantation.	2001 Feb 1	11157478
Determination of urinary methylated purine pattern by high-performance liquid chromatography.	2001 Feb 10	11232859
In situ kinetic characterization of methylthioadenosine transport by the adenosine transporter (P2) of the African Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense.	2001 Feb 15	11226379
Analysis of exonic splicing enhancers in the mouse gonadotropin-releasing hormone (GnRH) gene.	2001 Feb 28	11223187
The main products of the low molecular mass fraction in the venom of the spider Latrodectus menavodi.	2001 Feb-Mar	10978765
6-mercaptopurine dosage and pharmacokinetics influence the degree of bone marrow toxicity following high-dose methotrexate in children with acute lymphoblastic leukemia.	2001 Jan	11243403
Characterization of a triplex DNA-binding protein encoded by an alternative reading frame of loricrin.	2001 Jan	11168355
Effect of the tropical forage calliandra on microbial protein synthesis and ecology in the rumen.	2001 Jan	11155126
Purines inhibit poly(ADP-ribose) polymerase activation and modulate oxidant-induced cell death.	2001 Jan	11149897
Comparison of negative and positive ion electrospray tandem mass spectrometry for the liquid chromatography tandem mass spectrometry analysis of oxidized deoxynucleosides.	2001 Jan	11142363
Binding site of Fe3+ at purine of ATP as studied by NMR.	2001 Jan 15	11237248
The effect of folate deficiency on the cytotoxic and mutagenic responses to ethyl methanesulfonate in human lymphoblastoid cell lines that differ in p53 status.	2001 Jan 25	11166026
Purine nucleotide catabolism in rat liver: labelling of uric acid and allantoin after treatment with oxonic acid and allopurinol.	2001 Jan 26	11228097
Role of conserved nucleotides in building the 16 S rRNA binding site for ribosomal protein S15.	2001 Jan 26	11162092
Probing structure and dynamics of DNA with 2-aminopurine: effects of local environment on fluorescence.	2001 Jan 30	11170416
Cell cycle in the fucus zygote parallels a somatic cell cycle but displays a unique translational regulation of cyclin-dependent kinases.	2001 Mar	11251098
The protective effect of acadesine on lung ischemia-reperfusion injury.	2001 Mar	11226083
UCP1: the only protein able to mediate adaptive non-shivering thermogenesis and metabolic inefficiency.	2001 Mar 1	11239487
The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography.	2001 Mar 6	11258886
Novel treatment strategies in chronic lymphocytic leukemia.	2001 May	11296131
VX-497: a novel, selective IMPDH inhibitor and immunosuppressive agent.	2001 May	11288107

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:10:09 GMT 2023` Edited by `admin` on `Fri Dec 15 19:10:09 GMT 2023`
Record UNII	W60KTZ3IZY
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PURINE

Systematic Name

English

NSC-753

Code

English

1H-PURINE [MI]

Common Name

English

Classification Tree Code System Code

LOINC

85379-6