Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C8H15NO.ClH |
| Molecular Weight | 177.672 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CN1[C@H]2CC[C@@H]1C[C@@H](O)C2
InChI
InChIKey=ASWRTDCDFPALAX-AYNSSBQOSA-N
InChI=1S/C8H15NO.ClH/c1-9-6-2-3-7(9)5-8(10)4-6;/h6-8,10H,2-5H2,1H3;1H/t6-,7+,8-;
| Molecular Formula | C8H15NO |
| Molecular Weight | 141.2108 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Pseudotropine (ψ-tropine, or psi-tropine) is an isomer of tropine. Pseudotropine is formed during NADPH-dependent reduction of the 3-carbonyl group of tropinone to a beta-hydroxyl group. Tropinone reductase-II is an enzyme responsible for this transformation. It is known, that tropinone reductase-II is also a key enzyme in the biosynthetic pathway of tropane alkaloids, which include medicinally important compounds such as hyoscyamine (atropine) and cocaine.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Treatment of Cushing disease: overview and recent findings. | 2010-10-21 |
|
| The functional divergence of short-chain dehydrogenases involved in tropinone reduction. | 2008-05 |
|
| Quaternary derivatives of granatanol diesters: potent, ultrashort acting non-depolarizing neuromuscular relaxants. | 2006-07-04 |
|
| Calystegines in wild and cultivated Erythroxylum species. | 2005-06 |
|
| Structure-activity relationships among derivatives of dicarboxylic acid esters of tropine. | 2002-10 |
|
| Neuromuscular pharmacology of TAAC3, a new nondepolarizing muscle relaxant with rapid onset and ultrashort duration of action. | 2002-04 |
|
| The new neuromuscular blocking agents: do they offer any advantages? | 2001-12 |
|
| Virtual combinatorial syntheses and computational screening of new potential anti-herpes compounds. | 1999-08-26 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 23:04:24 GMT 2025
by
admin
on
Mon Mar 31 23:04:24 GMT 2025
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| Record UNII |
W43VJT02S4
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| Record Status |
Validated (UNII)
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| Record Version |
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6164-89-2
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DTXSID60362358
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m9300
Created by
admin on Mon Mar 31 23:04:24 GMT 2025 , Edited by admin on Mon Mar 31 23:04:24 GMT 2025
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PRIMARY | Merck Index |