Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C10H12N2O2 |
| Molecular Weight | 192.2145 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NCCC1=CNC2=CC(O)=C(O)C=C12
InChI
InChIKey=SKOKLDQYOKPCPU-UHFFFAOYSA-N
InChI=1S/C10H12N2O2/c11-2-1-6-5-12-8-4-10(14)9(13)3-7(6)8/h3-5,12-14H,1-2,11H2
| Molecular Formula | C10H12N2O2 |
| Molecular Weight | 192.2145 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Serotonin receptors are involved in the spinal mediation of descending facilitation of surgical incision-induced increase of Fos-like immunoreactivity in rats. | 2010-03-23 |
|
| Regeneration of 5-HT fibers in hippocampal heterotopia of methylazoxymethanol-induced micrencephalic rats after neonatal 5,7-DHT injection. | 2010-03 |
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| Histone H3 Acetylation is Asymmetrically Induced Upon Learning in Identified Neurons of the Food Aversion Network in the Mollusk Helix Lucorum. | 2010 |
|
| Response disengagement on a spatial self-ordered sequencing task: effects of regionally selective excitotoxic lesions and serotonin depletion within the prefrontal cortex. | 2009-05-06 |
|
| Interactions between dopamine and melatonin organize circadian rhythmicity in the retina of the green iguana. | 2007-12 |
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| Amphetamine and mCPP effects on dopamine and serotonin striatal in vivo microdialysates in an animal model of hyperactivity. | 2007-02 |
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| Comparative studies of the effects of chlorpromazine and 5,6-dihydroxytryptamine on locomotion, defensive reactions in the snail Helix lucorum, and command neuron excitability in long-term sensitization. | 2006-09 |
|
| Involvement of supraspinal imidazoline receptors and descending monoaminergic pathways in tizanidine-induced inhibition of rat spinal reflexes. | 2005-09 |
|
| [Comparative investigation of influence of injections of chlorpromazine and 5,6-dihydroxytryptamine on locomotion, defensive reactions of snall helix lucorum and excitability of command neurons in long-term sensitization]. | 2005-07 |
|
| Imidazoline receptors associated with noradrenergic terminals in the rostral ventrolateral medulla mediate the hypotensive responses of moxonidine but not clonidine. | 2005 |
|
| Opposite morphological responses of partially denervated cortical serotonergic and noradrenergic axons to repeated stress in adult rats. | 2004-07-30 |
|
| The 5-HT3 receptor facilitates at-level mechanical allodynia following spinal cord injury. | 2004-07 |
|
| Interaction between serotonergic and noradrenergic axons during axonal regeneration. | 2003-11 |
|
| Global 5-HT depletion attenuates the ability of amphetamine to decrease impulsive choice on a delay-discounting task in rats. | 2003-11 |
|
| Elimination of serotonergic cells induces a marked increase in generation of dopaminergic neurons from mesencephalic precursors. | 2003-10 |
|
| Electrophysiological studies of the effects of 5,6-dihydroxytryptamine on the acquisition of a conditioned defensive reflex in snails. | 2003-07 |
|
| Comparative effects of injecting 5,6-dihydroxytryptamine in the dorsal or medial raphe nuclei on rat puberty. | 2003-05-15 |
|
| 7-Hydroxytryptophan, a novel, specific, cytotoxic agent for carcinoids and other serotonin-producing tumors. | 2002-06-15 |
|
| Monoamine neurotoxins-induced apoptosis in lymphocytes by a common oxidative stress mechanism: involvement of hydrogen peroxide (H(2)O(2)), caspase-3, and nuclear factor kappa-B (NF-kappaB), p53, c-Jun transcription factors. | 2002-02-15 |
|
| [Electrophysiological study of 5,6-dihydroxytryptamine effect on defensive reflex conditioning in the snail]. | 2002-02 |
|
| Serotonin modulates expression of VIP and GRP mRNA via the 5-HT(1B) receptor in the suprachiasmatic nucleus of the rat. | 2001-10 |
|
| Studies on the behavioral and hypotensive effects of intraventricular prostacyclin (PGI2) in rats. | 1981-11 |
|
| Turning in MFB-lesioned rats and antagonism of neuroleptic-induced catalepsy after lisuride and LSD. | 1978-05-08 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:20:42 GMT 2025
by
admin
on
Mon Mar 31 19:20:42 GMT 2025
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| Record UNII |
W2QY253O8S
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| Record Status |
Validated (UNII)
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| Record Version |
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21163
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DTXSID40198930
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225-810-3
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5090-36-8
Created by
admin on Mon Mar 31 19:20:42 GMT 2025 , Edited by admin on Mon Mar 31 19:20:42 GMT 2025
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W2QY253O8S
Created by
admin on Mon Mar 31 19:20:42 GMT 2025 , Edited by admin on Mon Mar 31 19:20:42 GMT 2025
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PRIMARY |