Details
Stereochemistry | ACHIRAL |
Molecular Formula | C10H12N2O2 |
Molecular Weight | 192.2145 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
NCCC1=CNC2=C1C=C(O)C(O)=C2
InChI
InChIKey=SKOKLDQYOKPCPU-UHFFFAOYSA-N
InChI=1S/C10H12N2O2/c11-2-1-6-5-12-8-4-10(14)9(13)3-7(6)8/h3-5,12-14H,1-2,11H2
Molecular Formula | C10H12N2O2 |
Molecular Weight | 192.2145 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
PubMed
Title | Date | PubMed |
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Studies on the behavioral and hypotensive effects of intraventricular prostacyclin (PGI2) in rats. | 1981 Nov |
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Monoamine neurotoxins-induced apoptosis in lymphocytes by a common oxidative stress mechanism: involvement of hydrogen peroxide (H(2)O(2)), caspase-3, and nuclear factor kappa-B (NF-kappaB), p53, c-Jun transcription factors. | 2002 Feb 15 |
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7-Hydroxytryptophan, a novel, specific, cytotoxic agent for carcinoids and other serotonin-producing tumors. | 2002 Jun 15 |
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Electrophysiological studies of the effects of 5,6-dihydroxytryptamine on the acquisition of a conditioned defensive reflex in snails. | 2003 Jul |
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Comparative effects of injecting 5,6-dihydroxytryptamine in the dorsal or medial raphe nuclei on rat puberty. | 2003 May 15 |
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Interaction between serotonergic and noradrenergic axons during axonal regeneration. | 2003 Nov |
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Global 5-HT depletion attenuates the ability of amphetamine to decrease impulsive choice on a delay-discounting task in rats. | 2003 Nov |
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Elimination of serotonergic cells induces a marked increase in generation of dopaminergic neurons from mesencephalic precursors. | 2003 Oct |
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The 5-HT3 receptor facilitates at-level mechanical allodynia following spinal cord injury. | 2004 Jul |
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Opposite morphological responses of partially denervated cortical serotonergic and noradrenergic axons to repeated stress in adult rats. | 2004 Jul 30 |
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Imidazoline receptors associated with noradrenergic terminals in the rostral ventrolateral medulla mediate the hypotensive responses of moxonidine but not clonidine. | 2005 |
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[Comparative investigation of influence of injections of chlorpromazine and 5,6-dihydroxytryptamine on locomotion, defensive reactions of snall helix lucorum and excitability of command neurons in long-term sensitization]. | 2005 Jul |
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Comparative studies of the effects of chlorpromazine and 5,6-dihydroxytryptamine on locomotion, defensive reactions in the snail Helix lucorum, and command neuron excitability in long-term sensitization. | 2006 Sep |
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Interactions between dopamine and melatonin organize circadian rhythmicity in the retina of the green iguana. | 2007 Dec |
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Amphetamine and mCPP effects on dopamine and serotonin striatal in vivo microdialysates in an animal model of hyperactivity. | 2007 Feb |
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Response disengagement on a spatial self-ordered sequencing task: effects of regionally selective excitotoxic lesions and serotonin depletion within the prefrontal cortex. | 2009 May 6 |
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Histone H3 Acetylation is Asymmetrically Induced Upon Learning in Identified Neurons of the Food Aversion Network in the Mollusk Helix Lucorum. | 2010 |
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Regeneration of 5-HT fibers in hippocampal heterotopia of methylazoxymethanol-induced micrencephalic rats after neonatal 5,7-DHT injection. | 2010 Mar |
|
Serotonin receptors are involved in the spinal mediation of descending facilitation of surgical incision-induced increase of Fos-like immunoreactivity in rats. | 2010 Mar 23 |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 18:45:19 GMT 2023
by
admin
on
Fri Dec 15 18:45:19 GMT 2023
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Record UNII |
W2QY253O8S
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Record Status |
Validated (UNII)
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Record Version |
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21163
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DTXSID40198930
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225-810-3
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5090-36-8
Created by
admin on Fri Dec 15 18:45:19 GMT 2023 , Edited by admin on Fri Dec 15 18:45:19 GMT 2023
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W2QY253O8S
Created by
admin on Fri Dec 15 18:45:19 GMT 2023 , Edited by admin on Fri Dec 15 18:45:19 GMT 2023
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PRIMARY |