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Details

Stereochemistry ACHIRAL
Molecular Formula C10H12N2O2
Molecular Weight 192.2145
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 5,6-DIHYDROXYTRYPTAMINE

SMILES

NCCC1=CNC2=C1C=C(O)C(O)=C2

InChI

InChIKey=SKOKLDQYOKPCPU-UHFFFAOYSA-N
InChI=1S/C10H12N2O2/c11-2-1-6-5-12-8-4-10(14)9(13)3-7(6)8/h3-5,12-14H,1-2,11H2

HIDE SMILES / InChI

Molecular Formula C10H12N2O2
Molecular Weight 192.2145
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Studies on the behavioral and hypotensive effects of intraventricular prostacyclin (PGI2) in rats.
1981 Nov
Monoamine neurotoxins-induced apoptosis in lymphocytes by a common oxidative stress mechanism: involvement of hydrogen peroxide (H(2)O(2)), caspase-3, and nuclear factor kappa-B (NF-kappaB), p53, c-Jun transcription factors.
2002 Feb 15
7-Hydroxytryptophan, a novel, specific, cytotoxic agent for carcinoids and other serotonin-producing tumors.
2002 Jun 15
Electrophysiological studies of the effects of 5,6-dihydroxytryptamine on the acquisition of a conditioned defensive reflex in snails.
2003 Jul
Comparative effects of injecting 5,6-dihydroxytryptamine in the dorsal or medial raphe nuclei on rat puberty.
2003 May 15
Interaction between serotonergic and noradrenergic axons during axonal regeneration.
2003 Nov
Global 5-HT depletion attenuates the ability of amphetamine to decrease impulsive choice on a delay-discounting task in rats.
2003 Nov
Elimination of serotonergic cells induces a marked increase in generation of dopaminergic neurons from mesencephalic precursors.
2003 Oct
The 5-HT3 receptor facilitates at-level mechanical allodynia following spinal cord injury.
2004 Jul
Opposite morphological responses of partially denervated cortical serotonergic and noradrenergic axons to repeated stress in adult rats.
2004 Jul 30
Imidazoline receptors associated with noradrenergic terminals in the rostral ventrolateral medulla mediate the hypotensive responses of moxonidine but not clonidine.
2005
[Comparative investigation of influence of injections of chlorpromazine and 5,6-dihydroxytryptamine on locomotion, defensive reactions of snall helix lucorum and excitability of command neurons in long-term sensitization].
2005 Jul
Comparative studies of the effects of chlorpromazine and 5,6-dihydroxytryptamine on locomotion, defensive reactions in the snail Helix lucorum, and command neuron excitability in long-term sensitization.
2006 Sep
Interactions between dopamine and melatonin organize circadian rhythmicity in the retina of the green iguana.
2007 Dec
Amphetamine and mCPP effects on dopamine and serotonin striatal in vivo microdialysates in an animal model of hyperactivity.
2007 Feb
Response disengagement on a spatial self-ordered sequencing task: effects of regionally selective excitotoxic lesions and serotonin depletion within the prefrontal cortex.
2009 May 6
Histone H3 Acetylation is Asymmetrically Induced Upon Learning in Identified Neurons of the Food Aversion Network in the Mollusk Helix Lucorum.
2010
Regeneration of 5-HT fibers in hippocampal heterotopia of methylazoxymethanol-induced micrencephalic rats after neonatal 5,7-DHT injection.
2010 Mar
Serotonin receptors are involved in the spinal mediation of descending facilitation of surgical incision-induced increase of Fos-like immunoreactivity in rats.
2010 Mar 23
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 18:45:19 GMT 2023
Edited
by admin
on Fri Dec 15 18:45:19 GMT 2023
Record UNII
W2QY253O8S
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
5,6-DIHYDROXYTRYPTAMINE
Systematic Name English
1H-INDOLE-5,6-DIOL, 3-(2-AMINOETHYL)-
Systematic Name English
3-(2-AMINOETHYL)INDOLE-5,6-DIOL
Systematic Name English
INDOLE-5,6-DIOL, 3-(2-AMINOETHYL)-
Systematic Name English
Code System Code Type Description
PUBCHEM
21163
Created by admin on Fri Dec 15 18:45:19 GMT 2023 , Edited by admin on Fri Dec 15 18:45:19 GMT 2023
PRIMARY
EPA CompTox
DTXSID40198930
Created by admin on Fri Dec 15 18:45:19 GMT 2023 , Edited by admin on Fri Dec 15 18:45:19 GMT 2023
PRIMARY
ECHA (EC/EINECS)
225-810-3
Created by admin on Fri Dec 15 18:45:19 GMT 2023 , Edited by admin on Fri Dec 15 18:45:19 GMT 2023
PRIMARY
CAS
5090-36-8
Created by admin on Fri Dec 15 18:45:19 GMT 2023 , Edited by admin on Fri Dec 15 18:45:19 GMT 2023
PRIMARY
FDA UNII
W2QY253O8S
Created by admin on Fri Dec 15 18:45:19 GMT 2023 , Edited by admin on Fri Dec 15 18:45:19 GMT 2023
PRIMARY