BAMETHAN SULFATE

Details

Stereochemistry	RACEMIC
Molecular Formula	2C12H19NO2.H2O4S
Molecular Weight	516.648
Optical Activity	( + / - )
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OS(O)(=O)=O.CCCCNCC(O)C1=CC=C(O)C=C1.CCCCNCC(O)C2=CC=C(O)C=C2

InChI

InChIKey=PARMADWNFXEEFC-UHFFFAOYSA-N

InChI=1S/2C12H19NO2.H2O4S/c2*1-2-3-8-13-9-12(15)10-4-6-11(14)7-5-10;1-5(2,3)4/h2*4-7,12-15H,2-3,8-9H2,1H3;(H2,1,2,3,4)

HIDE SMILES / InChI

Molecular Formula	H2O4S
Molecular Weight	98.078
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C12H19NO2
Molecular Weight	209.2848
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.jstage.jst.go.jp/article/jsma1939/34/1/34_1_15/_pdf | https://www.ncbi.nlm.nih.gov/pubmed/4380496

Bamethan (butyl-sympatol or vasculat) is an adrenaline derivative developed by C. H. Boehringer Sohn. Bamethan shows a depressor action on peripheral blood vessels as a result of the peripheral vasodilating action caused by stimulation of adrenergic beta-receptor. Bamethan has been used abroad in the treatment of certain peripheral vascular and circulatory disturbances, such as vasospastic conditions, arteriosclerotic peripheral vascular disease, Raynaud's syndrome, occlusive vascular disease of the legs, the post-thrombotic syndrome, degenerative muscular disorders, and other conditions involving peripheral vascular insuffciency.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Adrenergic receptor beta 89 Target ID: CHEMBL2094118 Sources: https://www.ncbi.nlm.nih.gov/pubmed/4380496 \| https://www.ncbi.nlm.nih.gov/pubmed/4152789 \| https://www.jstage.jst.go.jp/article/jsma1939/34/1/34_1_15/_pdf	Agonist 2752

Conditions

Condition	Modality	Targets	Highest Phase	Product
Peripheral vascular insuffciency 5 Sources: http://www.ub.edu/pharmakoteka/node/26454 https://www.ncbi.nlm.nih.gov/pubmed/4380496	Primary		Approved 8583	VASCULAT Approved Use Bamethan has been used abroad in the treatment of certain peripheral vascular and circulatory disturbances, such as vasospastic conditions, arteriosclerotic peripheral vascular disease, Raynaud's syndrome, occlusive vascular disease of the legs, the post-thrombotic syndrome, degenerative muscular disorders, and other conditions involving peripheral vascular insuffciency.

Doses

Dose	Population	Adverse events
100 mg single, oral Studied dose Dose: 100 mg Route: oral Route: single Dose: 100 mg Sources: https://pubmed.ncbi.nlm.nih.gov/4380496/	healthy Health Status: healthy Sex: M+F Sources: https://pubmed.ncbi.nlm.nih.gov/4380496/	Sources: https://pubmed.ncbi.nlm.nih.gov/4380496/

PubMed

Title	Date	PubMed
Tandem mass spectrometry with online high-flow reversed-phase extraction and normal-phase chromatography on silica columns with aqueous-organic mobile phase for quantitation of polar compounds in biological fluids.	2005	16175657
Development and validation of a liquid chromatography/tandem mass spectrometry (LC/MS/MS) method for the determination of ribavirin in human plasma and serum.	2002-06-20	12062668
The effect of bamethan on cardiovascular response.	1966-01-01	4380496

Sample Use Guides

In Vivo Use Guide

75-100 mg

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:47:18 GMT 2025` Edited by `admin` on `Mon Mar 31 17:47:18 GMT 2025`
Record UNII	W2L3E1W827
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BASCURAT

Preferred Name

English

BAMETHAN SULFATE

Official Name

English

.ALPHA.-((BUTYLAMINO)METHYL)-P-HYDROXYBENZYL ALCOHOL SULFATE (2:1) (SALT)

Common Name

English

VASCULAT

Brand Name

English

BAMETHAN HEMISULFATE SALT

Common Name

English

BAMETHAN SULFATE [MART.]

Common Name

English

BUTYLNORSYMPATOL

Brand Name

English

BAMETHAN HEMISULFATE

Common Name

English

VASCULIT

Brand Name

English

BAMETHAN SULFATE [USAN]

Common Name

English

ECLERN

Brand Name

English

BAMETHAN SULFATE [MI]

Common Name

English

BAMETHAN SULFATE [JAN]

Common Name

English

BAMETHAN SULPHATE

Common Name

English

ROTESAR

Brand Name

English

.ALPHA.-((BUTYLAMINO)METHYL)-P-HYDROXYBENZYL ALCOHOL SULPHATE (2:1) (SALT)

Common Name

English

GARMIAN

Brand Name

English

BENZENEMETHANOL, .ALPHA.-((BUTYLAMINO)METHYL)-4-HYDROXY-, SULFATE (2:1) (SALT)

Common Name

English

BENZENEMETHANOL, .ALPHA.-((BUTYLAMINO)METHYL)-4-HYDROXY-, SULPHATE (2:1) (SALT)

Common Name

English

Bamethan sulfate [WHO-DD]

Common Name

English

BUPATOL

Brand Name

English

PERIPHETOL

Brand Name

English

BUTEDRIN

Brand Name

English

Classification Tree Code System Code

NCI_THESAURUS

C48149