CHLORDANTOIN

US Previously Marketed

First approved in 1960

Details

Stereochemistry	MIXED
Molecular Formula	C11H17Cl3N2O2S
Molecular Weight	347.689
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCC(CC)C1NC(=O)N(SC(Cl)(Cl)Cl)C1=O

InChI

InChIKey=VOGJJBHRUDVEFM-UHFFFAOYSA-N

InChI=1S/C11H17Cl3N2O2S/c1-3-5-6-7(4-2)8-9(17)16(10(18)15-8)19-11(12,13)14/h7-8H,3-6H2,1-2H3,(H,15,18)

HIDE SMILES / InChI

Molecular Formula	C11H17Cl3N2O2S
Molecular Weight	347.689
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13880002 | http://www.drugfuture.com/chemdata/Chlordantoin.html

CHLORDANTOIN, an imidazolidine-2,4-dione derivative, is a topical antifungal agent with activity against Candida albicans. It is used for the treatment of vaginal candidiasis.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Vulvovaginal Candidiasis 1 Sources: https://www.ncbi.nlm.nih.gov/pubmed/13880002 http://www.drugfuture.com/chemdata/Chlordantoin.html https://www.ncbi.nlm.nih.gov/pubmed/14144540	Curative		Approved 8429	Sporostacin Approved Use Vaginal candidiasis Launch Date -3.15619213E11

Sourcing

Vendor/Aggregator	ID	URL
001 Chemical	DY560440	https://www.001chemical.com/chem/5588-20-5
BLD Pharm	BD121920	http://www.bldpharm.com/products/5588-20-5.html
CSNpharm	CSN21572	https://www.csnpharm.com/products/chlordantoin.html
Chem Scene	CS-0018418	http://www.chemscene.com/5588-20-5.html
ChemMol	99117107	http://www.chemmol.com/chemmol/99117107.html
Chemspace	CSSB00020679258	https://chem-space.com/CSSB00020679258
MedChem Express	HY-100267	https://www.medchemexpress.com/Chlordantoin.html
Molcore	MC560440	https://www.molcore.com/product/5588-20-5
Smolecule	S580804	https://www.smolecule.com/products/s580804
THE BioTek	bt-368559	https://www.thebiotek.com/product/others/bt-368559

PubMed

Title	Date	PubMed
A new agent for the treatment of vaginal candidiasis.	1962 Mar 10	13880002
CLINICAL TRIALS WITH AGENTS CURRENTLY USED IN THE MANAGEMENT OF VAGINITIS.	1964 May 23	14144540
Miconazole nitrate compared with chlordantoin in the treatment of vaginal candidiasis.	1975 Apr	1093633

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:48:37 UTC 2023` Edited by `admin` on `Fri Dec 15 18:48:37 UTC 2023`
Record UNII	W14Z7581PA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CHLORDANTOIN

Official Name

English

CHLORDANTOIN [MI]

Common Name

English

5-(1-Ethylpentyl)-3-[(trichloromethyl)thio]hydantoin

Systematic Name

English

NSC-231427

Code

English

3-TRICHLOROMETHYLTHIO-5-(1-ETHYLAMYL)-HYDANTOIN

Systematic Name

English

2,4-IMIDAZOLIDINEDIONE, 5-(1-ETHYLPENTYL)-3-((TRICHLOROMETHYL)THIO)-

Systematic Name

English

CHLORDANTOIN [USAN]

Common Name

English

CLODANTOIN [MART.]

Common Name

English

CLODANTOIN

Official Name

English

HYDANTOIN, 5-(1-ETHYLPENTYL)-3-((TRICHLOROMETHYL)THIO)-

Systematic Name

English

clodantoin [INN]

Common Name

English

Clodantoin [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C514