CHLORDANTOIN

First approved in 1960

Details

Stereochemistry	MIXED
Molecular Formula	C11H17Cl3N2O2S
Molecular Weight	347.689
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCC(CC)C1NC(=O)N(SC(Cl)(Cl)Cl)C1=O

InChI

InChIKey=VOGJJBHRUDVEFM-UHFFFAOYSA-N

InChI=1S/C11H17Cl3N2O2S/c1-3-5-6-7(4-2)8-9(17)16(10(18)15-8)19-11(12,13)14/h7-8H,3-6H2,1-2H3,(H,15,18)

HIDE SMILES / InChI

Molecular Formula	C11H17Cl3N2O2S
Molecular Weight	347.689
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13880002 | http://www.drugfuture.com/chemdata/Chlordantoin.html

CHLORDANTOIN, an imidazolidine-2,4-dione derivative, is a topical antifungal agent with activity against Candida albicans. It is used for the treatment of vaginal candidiasis.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Vulvovaginal Candidiasis 1 Sources: https://www.ncbi.nlm.nih.gov/pubmed/13880002 http://www.drugfuture.com/chemdata/Chlordantoin.html https://www.ncbi.nlm.nih.gov/pubmed/14144540	Curative		Approved 8583	Sporostacin Approved Use Vaginal candidiasis Launch Date 1959

Sourcing

Vendor/Aggregator	ID	URL
001 Chemical	DY560440	https://www.001chemical.com/chem/5588-20-5
BLD Pharm	BD121920	http://www.bldpharm.com/products/5588-20-5.html
Chem Scene	CS-0018418	http://www.chemscene.com/5588-20-5.html
ChemMol	99117107	http://www.chemmol.com/chemmol/99117107.html
Chemspace	CSSB00020679258	https://chem-space.com/CSSB00020679258
CSNpharm	CSN21572	https://www.csnpharm.com/products/chlordantoin.html
MedChem Express	HY-100267	https://www.medchemexpress.com/Chlordantoin.html
Molcore	MC560440	https://www.molcore.com/product/5588-20-5
Smolecule	S580804	https://www.smolecule.com/products/s580804
THE BioTek	bt-368559	https://www.thebiotek.com/product/others/bt-368559

PubMed

Title	Date	PubMed
Miconazole nitrate compared with chlordantoin in the treatment of vaginal candidiasis.	1975-04	1093633
CLINICAL TRIALS WITH AGENTS CURRENTLY USED IN THE MANAGEMENT OF VAGINITIS.	1964-05-23	14144540
A new agent for the treatment of vaginal candidiasis.	1962-03-10	13880002

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:21:41 GMT 2025` Edited by `admin` on `Mon Mar 31 19:21:41 GMT 2025`
Record UNII	W14Z7581PA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CLODANTOIN

Preferred Name

English

CHLORDANTOIN

Official Name

English

CHLORDANTOIN [MI]

Common Name

English

5-(1-Ethylpentyl)-3-[(trichloromethyl)thio]hydantoin

Systematic Name

English

NSC-231427

Code

English

3-TRICHLOROMETHYLTHIO-5-(1-ETHYLAMYL)-HYDANTOIN

Systematic Name

English

2,4-IMIDAZOLIDINEDIONE, 5-(1-ETHYLPENTYL)-3-((TRICHLOROMETHYL)THIO)-

Systematic Name

English

CHLORDANTOIN [USAN]

Common Name

English

CLODANTOIN [MART.]

Common Name

English

HYDANTOIN, 5-(1-ETHYLPENTYL)-3-((TRICHLOROMETHYL)THIO)-

Systematic Name

English

clodantoin [INN]

Common Name

English

Clodantoin [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C514