U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 19:58:12 GMT 2023
Edited
by admin
on Sat Dec 16 19:58:12 GMT 2023
Protein Type NANOBODY
Protein Sub Type
Sequence Type COMPLETE
Record UNII
VYR5R5XN5A
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Lunsekimig
INN  
Official Name English
Immunoglobulin single chain of 5 VH (sc-5-VH), anti-[Homo sapiens IL13 (interleukin 13, IL-13)], anti-[Homo sapiens TSLP (thymic stromal lymphopoietin)] and anti-[Homo sapiens ALB (albumin, human serum albumin, HAS)], monoclonal antibody sc-5-VH, humaniz
Common Name English
Single chain of 5 VH (sc-5-VH) humanized and chimeric (1-671)[VH anti-IL13 chimeric Vicpac/Homsap (Vicugna pacos IGHV3-3*01 (87.6%) -(IGHD) -IGHJ2*01 (100%)/Homo sapiens IGHV3-23*04 (81.4%) -(IGHD) -IGHJ4*01 (85.7%), L50>R (45), CDR-IMGT [8.8.16] (26-33.
Common Name English
lunsekimig [INN]
Common Name English
Code System Code Type Description
CAS
2770858-49-4
Created by admin on Sat Dec 16 19:58:13 GMT 2023 , Edited by admin on Sat Dec 16 19:58:13 GMT 2023
PRIMARY
INN
12833
Created by admin on Sat Dec 16 19:58:13 GMT 2023 , Edited by admin on Sat Dec 16 19:58:13 GMT 2023
PRIMARY
FDA UNII
VYR5R5XN5A
Created by admin on Sat Dec 16 19:58:13 GMT 2023 , Edited by admin on Sat Dec 16 19:58:13 GMT 2023
PRIMARY
From To
1_595 1_647
1_565 1_641
1_441 1_515
1_315 1_388
1_180 1_254
1_22 1_96
Related Record Type Details
TARGET->LIGAND
TARGET->LIGAND
TARGET->LIGAND
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Anti-IL-13 PROTEIN FEATURE
Anti-TSLP (529F10) PROTEIN FEATURE
Anti-IL-13 (4B06) PROTEIN FEATURE
Anti-Albumin PROTEIN FEATURE
Molecular Formula CHEMICAL
Anti-TSLP PROTEIN FEATURE
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL