2'-HYDROXYCHALCONE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H12O2
Molecular Weight	224.2546
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of 2'-HYDROXYCHALCONE

Structure Search

SMILES

OC1=CC=CC=C1C(=O)\C=C\C2=CC=CC=C2

InChI

InChIKey=AETKQQBRKSELEL-ZHACJKMWSA-N

InChI=1S/C15H12O2/c16-14-9-5-4-8-13(14)15(17)11-10-12-6-2-1-3-7-12/h1-11,16H/b11-10+

HIDE SMILES / InChI

Molecular Formula	C15H12O2
Molecular Weight	224.2546
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Butyrylcholinesterase 45 Target ID: CHEMBL1914 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24780600	Inhibitor 8504		84.0 µM [IC50]

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:29:16 GMT 2025` Edited by `admin` on `Mon Mar 31 19:29:16 GMT 2025`
Record UNII	VY06DZ94OC
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NSC-170284

Preferred Name

English

2'-HYDROXYCHALCONE

Systematic Name

English

RVC-556

Code

English

2-PROPEN-1-ONE, 1-(2-HYDROXYPHENYL)-3-PHENYL-, (2E)-

Systematic Name

English

CHALCONE, 2'-HYDROXY-, (E)-

Systematic Name

English

2-PROPEN-1-ONE, 1-(2-HYDROXYPHENYL)-3-PHENYL-, (E)-

Systematic Name

English

NSC-18939

Code

English

1-(2-HYDROXYPHENYL)-3-PHENYL-2-PROPEN-1-ONE

Systematic Name

English

Code System Code Type Description

FDA UNII

VY06DZ94OC

Created by admin on Mon Mar 31 19:29:16 GMT 2025 , Edited by admin on Mon Mar 31 19:29:16 GMT 2025

PRIMARY

CAS

1214-47-7

Created by admin on Mon Mar 31 19:29:16 GMT 2025 , Edited by admin on Mon Mar 31 19:29:16 GMT 2025

NON-SPECIFIC STEREOCHEMISTRY

EPA CompTox

DTXSID001313416

Created by admin on Mon Mar 31 19:29:16 GMT 2025 , Edited by admin on Mon Mar 31 19:29:16 GMT 2025

PRIMARY

NSC

170284

Created by admin on Mon Mar 31 19:29:16 GMT 2025 , Edited by admin on Mon Mar 31 19:29:16 GMT 2025

PRIMARY

CAS

888-12-0

Created by admin on Mon Mar 31 19:29:16 GMT 2025 , Edited by admin on Mon Mar 31 19:29:16 GMT 2025

PRIMARY

PUBCHEM

638276

Created by admin on Mon Mar 31 19:29:16 GMT 2025 , Edited by admin on Mon Mar 31 19:29:16 GMT 2025

PRIMARY

CHEBI

27916

Created by admin on Mon Mar 31 19:29:16 GMT 2025 , Edited by admin on Mon Mar 31 19:29:16 GMT 2025

PRIMARY

NSC

18939

Created by admin on Mon Mar 31 19:29:16 GMT 2025 , Edited by admin on Mon Mar 31 19:29:16 GMT 2025

PRIMARY

ECHA (EC/EINECS)

212-962-0

Created by admin on Mon Mar 31 19:29:16 GMT 2025 , Edited by admin on Mon Mar 31 19:29:16 GMT 2025

PRIMARY

ECHA (EC/EINECS)

214-928-0

Created by admin on Mon Mar 31 19:29:16 GMT 2025 , Edited by admin on Mon Mar 31 19:29:16 GMT 2025

NON-SPECIFIC STEREOCHEMISTRY