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Details

Stereochemistry UNKNOWN
Molecular Formula C16H15F3O
Molecular Weight 280.2849
Optical Activity ( + )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FLUMECINOL, (+)-

SMILES

CCC(O)(C1=CC=CC=C1)C2=CC(=CC=C2)C(F)(F)F

InChI

InChIKey=DVASNQYQOZHAJN-UHFFFAOYSA-N
InChI=1S/C16H15F3O/c1-2-15(20,12-7-4-3-5-8-12)13-9-6-10-14(11-13)16(17,18)19/h3-11,20H,2H2,1H3

HIDE SMILES / InChI

Molecular Formula C16H15F3O
Molecular Weight 280.2849
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

FLUMECINOL, a benzhydrol derivative, is a hepatic microsomal drug-metabolizing enzyme inducer. It was in clinical development for the treatment of pruritus associated with primary biliary cirrhosis.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
PubMed

PubMed

TitleDatePubMed
[The drop in toxicity and the rise in the effectiveness of antineoplastic chemotherapy by correcting the activity of liver monooxygenases: from the experiment to the clinical practice].
2002
[Liver monooxygenase system inducers in the treatment of respiratory distress syndrome in newborn].
2002 Mar
Efficiency of enzyme-inducing agents in rats with intrahepatic cholestasis.
2002 Sep
[Efficacy of enzyme-inducing agents in experimental tetrachloromethane poisoning].
2003 Jul-Aug
Patents

Patents

Sample Use Guides

600 mg once weekly for 3 weeks.
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Sat Dec 16 11:07:28 UTC 2023
Edited
by admin
on Sat Dec 16 11:07:28 UTC 2023
Record UNII
VWK2338NBP
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FLUMECINOL, (+)-
Common Name English
BENZENEMETHANOL, .ALPHA.-ETHYL-.ALPHA.-PHENYL-3-(TRIFLUOROMETHYL)-, (+)-
Systematic Name English
(+)-FLUMECINOL
Systematic Name English
Code System Code Type Description
CAS
107317-30-6
Created by admin on Sat Dec 16 11:07:28 UTC 2023 , Edited by admin on Sat Dec 16 11:07:28 UTC 2023
PRIMARY
FDA UNII
VWK2338NBP
Created by admin on Sat Dec 16 11:07:28 UTC 2023 , Edited by admin on Sat Dec 16 11:07:28 UTC 2023
PRIMARY
PUBCHEM
41870
Created by admin on Sat Dec 16 11:07:28 UTC 2023 , Edited by admin on Sat Dec 16 11:07:28 UTC 2023
PRIMARY