U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Tue Apr 01 19:36:11 GMT 2025
Edited
by admin
on Tue Apr 01 19:36:11 GMT 2025
Source Materials Class ORGANISM
Source Materials Type VIRUS
Source Materials Parent
Part ns5b polymerase
Record UNII
VTC1801X29
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
HEPATITIS C NS5B POLYMERASE
Preferred Name English
HCV NS5B POLYMERASE
Common Name English
NONSTRUCTURAL PROTEIN 5B
Common Name English
NS5B POLYMERASE
Common Name English
NS5B
Common Name English
Code System Code Type Description
FDA UNII
VTC1801X29
Created by admin on Tue Apr 01 19:36:11 GMT 2025 , Edited by admin on Tue Apr 01 19:36:11 GMT 2025
PRIMARY
Related Record Type Details
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
NON-NUCLEOSIDE ACTIVE AGAINST ALL GENOTYPES
INHIBITOR -> TARGET
IC50
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
HCV replicon assays against full-length replicons from genotype 1a, 1b, 2a, 3a and 4a, and chimeric 1b replicons encoding NS5B from genotype 2b, 5a or 6a
IN-VITRO
EC50
INHIBITOR -> TARGET