U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Tue Apr 01 17:11:10 GMT 2025
Edited
by admin
on Tue Apr 01 17:11:10 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG2
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
VR8ERK4H7B
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PREZALUMAB
INN   WHO-DD  
INN  
Official Name English
prezalumab [INN]
Preferred Name English
AMG-557
Code English
MEDI-5872
Code English
IMMUNOGLOBULIN G2, ANTI-(HUMAN PROTEIN B7RP1 (B7-RELATED PROTEIN 1)) (HUMAN MONOCLONAL AMG 557 HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL AMG 557 LIGHT CHAIN, DIMER MANUAL REGISTRATION
Common Name English
Prezalumab [WHO-DD]
Common Name English
Code System Code Type Description
SMS_ID
300000021861
Created by admin on Tue Apr 01 17:11:10 GMT 2025 , Edited by admin on Tue Apr 01 17:11:10 GMT 2025
PRIMARY
NCI_THESAURUS
C170346
Created by admin on Tue Apr 01 17:11:10 GMT 2025 , Edited by admin on Tue Apr 01 17:11:10 GMT 2025
PRIMARY
ChEMBL
CHEMBL2109249
Created by admin on Tue Apr 01 17:11:10 GMT 2025 , Edited by admin on Tue Apr 01 17:11:10 GMT 2025
PRIMARY
CAS
1523164-68-2
Created by admin on Tue Apr 01 17:11:10 GMT 2025 , Edited by admin on Tue Apr 01 17:11:10 GMT 2025
PRIMARY
INN
10224
Created by admin on Tue Apr 01 17:11:10 GMT 2025 , Edited by admin on Tue Apr 01 17:11:10 GMT 2025
PRIMARY
FDA UNII
VR8ERK4H7B
Created by admin on Tue Apr 01 17:11:10 GMT 2025 , Edited by admin on Tue Apr 01 17:11:10 GMT 2025
PRIMARY
From To
1_230 2_230
1_227 2_227
1_224 2_224
1_223 2_223
2_135 4_214
1_135 3_214
4_134 4_194
4_23 4_88
3_134 3_194
3_23 3_88
2_367 2_425
2_261 2_321
2_148 2_204
2_22 2_96
1_367 1_425
1_261 1_321
1_148 1_204
1_22 1_96
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_297
N 2_297
Related Record Type Details
B-7 RELATED PROTEIN 1
TARGET -> INHIBITOR
Related Record Type Details
PREZALUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:SEQUENCE(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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