PREZALUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 11:51:38 GMT 2023` Edited by `admin` on `Sat Dec 16 11:51:38 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG2
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	VR8ERK4H7B
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PREZALUMAB

Official Name

English

AMG-557

Code

English

prezalumab [INN]

Common Name

English

MEDI-5872

Code

English

MEDI 5872 [WHO-DD]

Common Name

English

IMMUNOGLOBULIN G2, ANTI-(HUMAN PROTEIN B7RP1 (B7-RELATED PROTEIN 1)) (HUMAN MONOCLONAL AMG 557 HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL AMG 557 LIGHT CHAIN, DIMER MANUAL REGISTRATION

Common Name

English

Prezalumab [WHO-DD]

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C170346

Created by admin on Sat Dec 16 11:51:38 GMT 2023 , Edited by admin on Sat Dec 16 11:51:38 GMT 2023

PRIMARY

ChEMBL

CHEMBL2109249

Created by admin on Sat Dec 16 11:51:38 GMT 2023 , Edited by admin on Sat Dec 16 11:51:38 GMT 2023

PRIMARY

CAS

1523164-68-2

Created by admin on Sat Dec 16 11:51:38 GMT 2023 , Edited by admin on Sat Dec 16 11:51:38 GMT 2023

PRIMARY

INN

10224

Created by admin on Sat Dec 16 11:51:38 GMT 2023 , Edited by admin on Sat Dec 16 11:51:38 GMT 2023

PRIMARY

FDA UNII

VR8ERK4H7B

Created by admin on Sat Dec 16 11:51:38 GMT 2023 , Edited by admin on Sat Dec 16 11:51:38 GMT 2023

PRIMARY

From	To
1_230	2_230
1_227	2_227
1_224	2_224
1_223	2_223
2_135	4_214
1_135	3_214
4_134	4_194
4_23	4_88
3_134	3_194
3_23	3_88
2_367	2_425
2_261	2_321
2_148	2_204
2_22	2_96
1_367	1_425
1_261	1_321
1_148	1_204
1_22	1_96

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_297
N	2_297

Related Record Type Details


					3PG6HL5J26

B-7 RELATED PROTEIN 1

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					VR8ERK4H7B

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:SEQUENCE(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL