U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 20:12:45 GMT 2023
Edited
by admin
on Sat Dec 16 20:12:45 GMT 2023
Protein Type ION CHANNEL
Protein Sub Type SODIUM ION CHANNEL
Sequence Origin RAT
Sequence Type COMPLETE
Record UNII
VR2UW942MF
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Sodium channel protein type 4 subunit alpha (Rat)
Common Name English
Voltage-gated sodium channel subunit alpha Nav1.4 (Rat)
Common Name English
Sodium channel protein type IV subunit alpha (Rat)
Common Name English
Sodium channel protein skeletal muscle subunit alpha (Rat)
Common Name English
Scn4a (Rat)
Common Name English
Code System Code Type Description
UNIPROT
P15390
Created by admin on Sat Dec 16 20:12:45 GMT 2023 , Edited by admin on Sat Dec 16 20:12:45 GMT 2023
PRIMARY
FDA UNII
VR2UW942MF
Created by admin on Sat Dec 16 20:12:45 GMT 2023 , Edited by admin on Sat Dec 16 20:12:45 GMT 2023
PRIMARY
Related Record Type Details
INHIBITOR -> TARGET
BN82451 was evaluated on binding of [3H]batrachotoxinin A 20-alpha-benzoate to neurotoxin re-ceptor site 2 in rat cortex membrane preparations (veratridine site). In this assay, BN82451 inhibits the binding of [3H]batrachotoxinin A in a concentration-dependent manner.
IC50
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL