LONOCTOCOG ALFA

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

US Approved Rx (2016)

First approved in 2016

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 21:53:13 GMT 2025` Edited by `admin` on `Mon Mar 31 21:53:13 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	VQ723R7O8R
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ANTIHEMOPHILIC FACTOR (RECOMBINANT), SINGLE CHAIN

Preferred Name

English

LONOCTOCOG ALFA

Official Name

English

AFSTYLA

Brand Name

English

Lonoctocog alfa [WHO-DD]

Common Name

English

CSL627

Code

English

LONOCTOCOG ALFA [MI]

Common Name

English

LONOCTOCOG ALFA [JAN]

Common Name

English

RVIII-SINGLECHAIN

Common Name

English

lonoctocog alfa [INN]

Common Name

English

CSL-627

Code

English

Code System Code Type Description

SMS_ID

100000163010

Created by admin on Mon Mar 31 21:53:13 GMT 2025 , Edited by admin on Mon Mar 31 21:53:13 GMT 2025

PRIMARY

MERCK INDEX

m12091

Created by admin on Mon Mar 31 21:53:13 GMT 2025 , Edited by admin on Mon Mar 31 21:53:13 GMT 2025

PRIMARY

CAS

1388129-63-2

Created by admin on Mon Mar 31 21:53:13 GMT 2025 , Edited by admin on Mon Mar 31 21:53:13 GMT 2025

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DRUG BANK

DB13998

Created by admin on Mon Mar 31 21:53:13 GMT 2025 , Edited by admin on Mon Mar 31 21:53:13 GMT 2025

PRIMARY

DRUG CENTRAL

5265

Created by admin on Mon Mar 31 21:53:13 GMT 2025 , Edited by admin on Mon Mar 31 21:53:13 GMT 2025

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FDA UNII

VQ723R7O8R

Created by admin on Mon Mar 31 21:53:13 GMT 2025 , Edited by admin on Mon Mar 31 21:53:13 GMT 2025

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EVMPD

SUB177134

Created by admin on Mon Mar 31 21:53:13 GMT 2025 , Edited by admin on Mon Mar 31 21:53:13 GMT 2025

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DAILYMED

VQ723R7O8R

Created by admin on Mon Mar 31 21:53:13 GMT 2025 , Edited by admin on Mon Mar 31 21:53:13 GMT 2025

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RXCUI

1796377

Created by admin on Mon Mar 31 21:53:13 GMT 2025 , Edited by admin on Mon Mar 31 21:53:13 GMT 2025

PRIMARY

INN

9834

Created by admin on Mon Mar 31 21:53:13 GMT 2025 , Edited by admin on Mon Mar 31 21:53:13 GMT 2025

PRIMARY

NCI_THESAURUS

C170127

Created by admin on Mon Mar 31 21:53:13 GMT 2025 , Edited by admin on Mon Mar 31 21:53:13 GMT 2025

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From	To
1_153	1_179
1_248	1_329
1_528	1_554
1_630	1_711
1_944	1_970
1_1011	1_1015
1_1133	1_1281
1_1286	1_1438

Glycosylation Link Type	Site
N	1_41
N	1_239
N	1_757
N	1_764
N	1_922
N	1_1230
O	1_743

Related Record Type Details


					VQ723R7O8R

LONOCTOCOG ALFA

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_346] [1_718] [1_719] [1_723] [1_776] [1_792]		Tyr		TYROSINE O-SULFATE	29166358BF

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL