Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Wed Apr 02 19:08:05 GMT 2025
by
admin
on
Wed Apr 02 19:08:05 GMT 2025
|
| Protein Type | ION CHANNEL |
| Protein Sub Type | POTASSIUM CHANNEL |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
VPD2Z47JYQ
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
Q15842
Created by
admin on Wed Apr 02 19:08:05 GMT 2025 , Edited by admin on Wed Apr 02 19:08:05 GMT 2025
|
PRIMARY | |||
|
O60706
Created by
admin on Wed Apr 02 19:08:05 GMT 2025 , Edited by admin on Wed Apr 02 19:08:05 GMT 2025
|
PRIMARY | |||
|
VPD2Z47JYQ
Created by
admin on Wed Apr 02 19:08:05 GMT 2025 , Edited by admin on Wed Apr 02 19:08:05 GMT 2025
|
PRIMARY |
| Glycosylation Type | HUMAN |
| Glycosylation Link Type | Site |
|---|---|
| N | 1_9 |
| N | 1_280 |
| N | 1_326 |
| N | 1_330 |
| N | 1_333 |
| N | 1_402 |
| N | 1_735 |
| N | 1_763 |
| N | 1_769 |
| N | 1_811 |
| N | 1_966 |
| N | 1_1025 |
| N | 1_1448 |
| N | 2_9 |
| N | 2_280 |
| N | 2_326 |
| N | 2_330 |
| N | 2_333 |
| N | 2_402 |
| N | 2_735 |
| N | 2_763 |
| N | 2_769 |
| N | 2_811 |
| N | 2_966 |
| N | 2_1025 |
| N | 2_1448 |
| N | 3_9 |
| N | 3_280 |
| N | 3_326 |
| N | 3_330 |
| N | 3_333 |
| N | 3_402 |
| N | 3_735 |
| N | 3_763 |
| N | 3_769 |
| N | 3_811 |
| N | 3_966 |
| N | 3_1025 |
| N | 3_1448 |
| N | 4_9 |
| N | 4_280 |
| N | 4_326 |
| N | 4_330 |
| N | 4_333 |
| N | 4_402 |
| N | 4_735 |
| N | 4_763 |
| N | 4_769 |
| N | 4_811 |
| N | 4_966 |
| N | 4_1025 |
| N | 4_1448 |
| N | 5_389 |
| N | 5_395 |
| N | 5_401 |
| N | 5_420 |
| N | 6_389 |
| N | 6_395 |
| N | 6_401 |
| N | 6_420 |
| N | 7_389 |
| N | 7_395 |
| N | 7_401 |
| N | 7_420 |
| N | 8_389 |
| N | 8_395 |
| N | 8_401 |
| N | 8_420 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
ACTIVATOR -> TARGET |
Opens potassium channel. Test done in Guinea pigs bladder muscle. Inhibition of action potentials and phasic contractions of UBSM. The results suggest that activation of <1% of KATP channels is sufficient to inhibit significantly action potentials and the related phasic contractions.
K1/2
|
||
|
ACTIVATOR -> TARGET |
Opens potassium channel. Test done in Guinea pigs bladder muscle. Half maximal activation of potassium current.
K1/2
|
||
|
INHIBITOR -> TARGET |
|
||
|
ACTIVATOR -> TARGET |
Potassium channel opener
|
||
|
|
INHIBITOR -> TARGET |
Selective for Kir6.1/Sur2b potassium channel
IC50
|
||
|
ACTIVATOR -> TARGET |
Opens potassium channel. Test done in Guinea pigs bladder muscle. Inhibition of action potentials and phasic contractions of UBSM. The results suggest that activation of <1% of KATP channels is sufficient to inhibit significantly action potentials and the related phasic contractions.
K1/2
|
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| Molecular Formula | CHEMICAL |
|
||||
| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
|