CTCE-0214

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 14:38:35 GMT 2023` Edited by `admin` on `Sat Dec 16 14:38:35 GMT 2023`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	VOY9490C9O
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CTCE-0214

Code

English

L-ASPARTAMIDE, L-LYSYL-L-PROLYL-L-VALYL-L-SERYL-L-LEUCYL-L-SERYL-L-TYROSYL-L-ARGINYL-L-ALANYL-L-PROLYL-L-PHENYLALANYL-L-ARGINYL-L-PHENYLALANYL-L-PHENYLALANYLGLYCYLGLYCYLGLYCYLGLYCYL-L-LEUCYL-L-LYSYL-L-TRYPTOPHYL-L-ISOLEUCYL-L-GLUTAMINYL-L-.ALPHA.-GLUTAMY

Systematic Name

English

CTCE 0214

Code

English

CT-0214

Code

English

LYS-PRO-VAL-SER-LEU-SER-TYR-ARG-ALA-PRO-PHE-ARG-PHE-PHE-GLY-GLY-GLY-GLY-LEU-LYS-TRP-ILE-GLN-GLU-TYR-LEU-GLU-LYS-ALA-LEU-ASN (24->20)-LACTAM

Systematic Name

English

Code System Code Type Description

FDA UNII

VOY9490C9O

Created by admin on Sat Dec 16 14:38:35 GMT 2023 , Edited by admin on Sat Dec 16 14:38:35 GMT 2023

PRIMARY

DRUG BANK

DB05934

Created by admin on Sat Dec 16 14:38:35 GMT 2023 , Edited by admin on Sat Dec 16 14:38:35 GMT 2023

PRIMARY

CAS

577782-52-6

Created by admin on Sat Dec 16 14:38:35 GMT 2023 , Edited by admin on Sat Dec 16 14:38:35 GMT 2023

PRIMARY

Linkage Type	Residue Index
LACTAM	1_20	1_24

Related Record Type Details


					VOY9490C9O

CTCE-0214

ACTIVE MOIETY

Comments:

CTCE-0214 is often a steady peptide agonist of stromal cell-derived factor-1 (SDF-1), a important signaling molecule while in the proliferation, homing, engraftment and growth of hematopoietic stem cells and white blood cells. SDF-1 is also thought to get the job done as being a visitors controller for infection-fighting white blood cells and progenitor cell migration supplying an important operate to fight immunosuppression. CTCE-0214, primarily based on Chemokines preclinical research, mimics the exercise with the healthy chemokine SDF-1 by rising the stage of white blood cells (neutrophils), bleeding prevention cells (platelets) and stem cells (primitive blood forming cells) while in the blood. These findings happen to be confirmed by way of impartial laboratories at Memorial Sloan Kettering Cancer middle and Cornell health-related college in New York along with the Walther Cancer Institute in Indianapolis.

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL