U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C6H15N
Molecular Weight 101.19
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Triethylamine

SMILES

CCN(CC)CC

InChI

InChIKey=ZMANZCXQSJIPKH-UHFFFAOYSA-N
InChI=1S/C6H15N/c1-4-7(5-2)6-3/h4-6H2,1-3H3

HIDE SMILES / InChI

Molecular Formula C6H15N
Molecular Weight 101.19
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Cmax

Cmax

ValueDoseCo-administeredAnalytePopulation
1.17 μM
25 mg single, oral
dose: 25 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
TRIETHYLAMINE plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: MALE
food status: FASTED
AUC

AUC

ValueDoseCo-administeredAnalytePopulation
5.46 μM × h
25 mg single, oral
dose: 25 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
TRIETHYLAMINE plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: MALE
food status: FASTED
3.81 μM × h
137 μmol single, intravenous
dose: 137 μmol
route of administration: Intravenous
experiment type: SINGLE
co-administered:
TRIETHYLAMINE plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
T1/2

T1/2

ValueDoseCo-administeredAnalytePopulation
2.9 h
25 mg single, oral
dose: 25 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
TRIETHYLAMINE plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: MALE
food status: FASTED
3.7 h
137 μmol single, intravenous
dose: 137 μmol
route of administration: Intravenous
experiment type: SINGLE
co-administered:
TRIETHYLAMINE plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
PubMed

PubMed

TitleDatePubMed
Polyallylamine-grafted cellulose gel as high-capacity anion-exchanger.
2002-02-08
Simultaneous determination of cloricromene and its active metabolite in rabbit aqueous humor by high-performance liquid chromatography.
2002-02-05
Not all 'predator odours' are equal: cat odour but not 2,4,5 trimethylthiazoline (TMT; fox odour) elicits specific defensive behaviours in rats.
2002-02-01
First- and second- sphere coordination of the uranyl ion by bis[2-(2-hydroxyphenoxy)ethoxy]ethane.
2002-02
Rapid determination of pseudoephedrine in human plasma by high-performance liquid chromatography.
2002-01-25
Process design for efficient and controlled drug incorporation into polymeric micelle carrier systems.
2002-01-17
Borderline between E1cB and E2 mechanisms. Chlorine isotope effects in base-promoted elimination Reactions.
2002-01-11
High-performance liquid chromatographic analysis of a new neuroprotective agent for ischemia-reperfusion damage, KR-31378.
2002-01-05
Fluorescent labeling of drugs and simple organic compounds containing amine functional groups, utilizing dansyl chloride in Na(2)CO(3) buffer.
2002-01-05
Excited state proton transfer reaction of two new intramolecularly hydrogen bonded Schiff bases at room temperature and 77K.
2002-01-01
A new HPLC method to determine Donepezil hydrochloride in tablets.
2002-01-01
Mechanism of response enhancement in evaporative light scattering detection with the addition of triethylamine and formic acid.
2002-01
Reactions of oxalyl chloride with 1,2-cycloalkanediols in the presence of triethylamine.
2002-01
Immobilization of the hydantoin cleaving enzymes from Arthrobacter aurescens DSM 3747.
2001-12-28
Determination of haloacetic acids in aqueous environments by solid-phase extraction followed by ion-pair liquid chromatography-electrospray ionization mass spectrometric detection.
2001-12-14
Clean-up procedures for the analysis of heterocyclic aromatic amines (aminoazaarenes) from heat-treated meat samples.
2001-12-14
The reactions of diaminomaleonitrile with isocyanates and either aldehydes or ketones revisited.
2001-12-14
Determination of propranolol concentration in small volume of rat plasma by HPLC with fluorometric detection.
2001-12
Quality of odor and olfactory lateralization processes in humans.
2001-12
Ionic blockade of the rat connexin40 gap junction channel by large tetraalkylammonium ions.
2001-12
Simultaneous determination of tolperisone and lidocaine by high performance liquid chromatography.
2001-12
On-line capillary electrophoresis with mass spectrometry detection for the analysis of carbohydrates after derivatization with 8-aminonaphthalene-1,3,6-trisulfonic acid.
2001-11-16
Impact of triethylamine as a mobile phase additive on the resolution of racemic amino acids on an (+)-18-crown-6-tetracarboxylic acid-derived chiral stationary phase.
2001-11-09
Synthesis of 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)adenine (FddA) via a purine 3'-deoxynucleoside.
2001-11-02
Analysis of polymerase chain reaction products by on-line liquid chromatography-mass spectrometry for genotyping of polymorphic short tandem repeat loci.
2001-11-01
Capillary electrochromatography analysis of hormonal cyclic and linear peptides.
2001-10-15
Switch-over in photochemical reaction mechanism from hydrogen abstraction to exciplex-induced quenching: interaction of triplet-excited versus singlet-excited acetone versus cumyloxyl radicals with amines.
2001-10-10
Development of sensitive high-performance liquid chromatography with fluorescence detection using 4-(4,5-diphenyl-1H-imidazol-2-yl)-benzoyl chloride as a labeling reagent for determination of bisphenol A in plasma samples.
2001-10-05
A dendritic active site: catalysis of the Henry reaction.
2001-10-04
Quenching effect of triethylamine on peroxyoxalate chemiluminescence in the presence of 7-amino-4-trifluoromethylcumarin.
2001-10
A psychophysical study of the relationship between temporal processing in odor mixtures and transduction pathways.
2001-10
Quantification of metronidazole in small-volume biological samples using narrow-bore high-performance liquid chromatography.
2001-09-25
Quantification of epimeric budesonide and fluticasone propionate in human plasma by liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry.
2001-09-25
Simultaneous determination of ingredients in an ointment by hydrophobic interaction electrokinetic chromatography.
2001-09-21
Assessment of the retention properties of poly(vinyl alcohol) stationary phase for lipid class profiling in liquid chromatography.
2001-09-14
Palladium-catalyzed tandem dimerization and cyclization of acetylenic ketones: a convenient method for 3,3'-bifurans using PdCl2(PPh3)2.
2001-09-07
Development of a simplified, sensitive high-performance liquid chromatographic method using fluorescence detection to determine the concentration of UCN-01 in human plasma.
2001-09-05
Rapid and sensitive high-performance liquid chromatographic method for the determination of ritonavir in human plasma.
2001-09
The aquatic fate of triclopyr in whole-pond treatments.
2001-09
Separation of some mono-, di- and tri-unsaturated fatty acids containing 18 carbon atoms by high-performance liquid chromatography and photodiode array detection.
2001-08-25
Comparison of L-tryptophan binding capacity of BSA captured by a polymer brush with that of BSA adsorbed onto a gel network.
2001-08-03
[Synthesis of phosphoramide mustard analogues belonging to the L-sugar series].
2001-08
Enantiomer separation by nonaqueous and aqueous capillary electrochromatography on cyclodextrin stationary phases.
2001-08
Separation of lidocaine and its metabolites by capillary electrophoresis using volatile aqueous and nonaqueous electrolyte systems.
2001-08
An improved (32)P-postlabeling assay for the sensitive detection of 8-oxodeoxyguanosine in tissue DNA.
2001-08
PH-Zone-refining counter-current chromatography of lappaconitine from Aconitum sinomontanum nakai I. Separation of prepurified extract.
2001-07-20
Three-step synthesis of (R)- and (S)-thalidomides from ornithine.
2001
Discrimination of three mutational events that result in a disruption of the R122 primary autolysis site of the human cationic trypsinogen (PRSS1) by denaturing high performance liquid chromatography.
2001
Cell adhesion and signaling on the fibronectin 1st type III repeat; requisite roles for cell surface proteoglycans and integrins.
2001
Oriented antibody immobilization to polystyrene macrocarriers for immunoassay modified with hydrazide derivatives of poly(meth)acrylic acid.
2001
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:49:26 GMT 2025
Edited
by admin
on Mon Mar 31 17:49:26 GMT 2025
Record UNII
VOU728O6AY
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FEMA NO. 4246
Preferred Name English
Triethylamine
FHFI   HSDB   MI   USP-RS  
Systematic Name English
ETHANAMINE, N,N-DIETHYL-
Systematic Name English
TRIETHYLAMINE [MI]
Common Name English
TRIETHYLAMINE [FHFI]
Common Name English
N,N-DIETHYLETHANAMINE
Systematic Name English
TRIETHYLAMINE [USP-RS]
Common Name English
(DIETHYLAMINO)ETHANE
Systematic Name English
TRIETHYLAMINE [HSDB]
Common Name English
Classification Tree Code System Code
JECFA EVALUATION TRIETHYLAMINE
Created by admin on Mon Mar 31 17:49:26 GMT 2025 , Edited by admin on Mon Mar 31 17:49:26 GMT 2025
Code System Code Type Description
SMS_ID
100000156649
Created by admin on Mon Mar 31 17:49:26 GMT 2025 , Edited by admin on Mon Mar 31 17:49:26 GMT 2025
PRIMARY
DAILYMED
VOU728O6AY
Created by admin on Mon Mar 31 17:49:26 GMT 2025 , Edited by admin on Mon Mar 31 17:49:26 GMT 2025
PRIMARY
ECHA (EC/EINECS)
204-469-4
Created by admin on Mon Mar 31 17:49:26 GMT 2025 , Edited by admin on Mon Mar 31 17:49:26 GMT 2025
PRIMARY
HSDB
896
Created by admin on Mon Mar 31 17:49:26 GMT 2025 , Edited by admin on Mon Mar 31 17:49:26 GMT 2025
PRIMARY
RXCUI
1307097
Created by admin on Mon Mar 31 17:49:26 GMT 2025 , Edited by admin on Mon Mar 31 17:49:26 GMT 2025
PRIMARY RxNorm
PUBCHEM
8471
Created by admin on Mon Mar 31 17:49:26 GMT 2025 , Edited by admin on Mon Mar 31 17:49:26 GMT 2025
PRIMARY
MESH
C016162
Created by admin on Mon Mar 31 17:49:26 GMT 2025 , Edited by admin on Mon Mar 31 17:49:26 GMT 2025
PRIMARY
WIKIPEDIA
TRIETHYLAMINE
Created by admin on Mon Mar 31 17:49:26 GMT 2025 , Edited by admin on Mon Mar 31 17:49:26 GMT 2025
PRIMARY
CAS
121-44-8
Created by admin on Mon Mar 31 17:49:26 GMT 2025 , Edited by admin on Mon Mar 31 17:49:26 GMT 2025
PRIMARY
CHEBI
35026
Created by admin on Mon Mar 31 17:49:26 GMT 2025 , Edited by admin on Mon Mar 31 17:49:26 GMT 2025
PRIMARY
FDA UNII
VOU728O6AY
Created by admin on Mon Mar 31 17:49:26 GMT 2025 , Edited by admin on Mon Mar 31 17:49:26 GMT 2025
PRIMARY
EVMPD
SUB130556
Created by admin on Mon Mar 31 17:49:26 GMT 2025 , Edited by admin on Mon Mar 31 17:49:26 GMT 2025
PRIMARY
EPA CompTox
DTXSID3024366
Created by admin on Mon Mar 31 17:49:26 GMT 2025 , Edited by admin on Mon Mar 31 17:49:26 GMT 2025
PRIMARY
RS_ITEM_NUM
1683559
Created by admin on Mon Mar 31 17:49:26 GMT 2025 , Edited by admin on Mon Mar 31 17:49:26 GMT 2025
PRIMARY
JECFA MONOGRAPH
1600
Created by admin on Mon Mar 31 17:49:26 GMT 2025 , Edited by admin on Mon Mar 31 17:49:26 GMT 2025
PRIMARY
MERCK INDEX
m11101
Created by admin on Mon Mar 31 17:49:26 GMT 2025 , Edited by admin on Mon Mar 31 17:49:26 GMT 2025
PRIMARY Merck Index
Related Record Type Details
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT