M-DIFLUOROBENZENE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H4F2
Molecular Weight	114.0928
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

FC1=CC(F)=CC=C1

InChI

InChIKey=UEMGWPRHOOEKTA-UHFFFAOYSA-N

InChI=1S/C6H4F2/c7-5-2-1-3-6(8)4-5/h1-4H

HIDE SMILES / InChI

Molecular Formula	C6H4F2
Molecular Weight	114.0928
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.	2001 Aug 2	11472208
(E)-1-(2'-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-(2-iodovinyl)benzene.	2001 Jun	11408697
7-Chloro-1-(2,6-difluorophenyl)-1H,3H-thiazolo.	2001 May	11353255
Synthesis and antibacterial activity of some novel N-substituted piperazinyl-quinolones.	2001 Nov-Dec	11822230
Synthesis and antitumor activity of novel pyrimidinyl pyrazole derivatives. II. Optimization of the phenylpiperazine moiety of 1-[5-methyl-1-(2-pyrimidinyl)-4-pyrazolyl]-3-phenylpiperazinyl-1-trans-propenes.	2002 Apr	11963990
Living polymerization of ethylene catalyzed by titanium complexes having fluorine-containing phenoxy-imine chelate ligands.	2002 Apr 3	11916417
Iminopropadienones from dioxanediones, isoxazolopyrimidinones, pyridopyrimidinones, and pyridopyrimidinium olates.	2002 Nov 29	12444639
Synthesis and characterization of (octaaryltetraazaporphyrinato)indium(III) complexes for optical limiting.	2003 Apr 21	12691576
1H-Pyrazolo[3,4-b]pyridine inhibitors of cyclin-dependent kinases: highly potent 2,6-Difluorophenacyl analogues.	2003 Jul 21	12824044
Adverse drug reactions: implications for the development of fluoroquinolones.	2003 May	12702700
The effect of universal fluorinated nucleobases on the catalytic activity of ribozymes.	2003 May-Aug	14565415
Synthesis of 1-triazolyl-4-trimethylsilyl-2-butanol and 1-triazolyl-5-trimethylsilyl-2-pentanol derivatives and an investigation of their fungicidal activities.	2003 Sep	12951461
Marked effect of aromatic solvent on unfolding rate of helical ethynylhelicene oligomer.	2004 Nov 17	15535712
Synthesis and purification of fluorinated benzimidazole and benzene nucleoside-5'-triphosphates.	2005	16248006
Design, synthesis, and biological evaluation of N-acetyl-2-carboxybenzenesulfonamides: a novel class of cyclooxygenase-2 (COX-2) inhibitors.	2005 Apr 1	15755648
Antimicrobial safety: focus on fluoroquinolones.	2005 Jul 15	15942881
Photodissociation dynamics of C6HxF6-x (x = 1-4) at 193 nm.	2005 May 5	16851978
Design, synthesis, and biological evaluation of (E)-3-(4-methanesulfonylphenyl)-2-(aryl)acrylic acids as dual inhibitors of cyclooxygenases and lipoxygenases.	2006 Dec 1	16931030
Novel synthesis of desymmetrized resorcinol derivatives: aryl fluoride displacement on deactivated substrates.	2006 Mar 3	16497012
Fluorinated diphenylpolyenes: crystal structures and emission properties.	2007 Dec 27	18052354
5,10,15,20-Tetra-kis(3,5-difluoro-phen-yl)porphyrin.	2007 Dec 6	21200755
Dinuclear iron complexes based on parallel beta-diiminato binding sites: syntheses, structures and reaction with O2.	2008 Apr 14	18369499
Adsorption of benzene, fluorobenzene and meta-di-fluorobenzene on Cu(110): a computational study.	2008 Jul 30	18293307
Synthesis, cannabinoid receptor affinity, and molecular modeling studies of substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides.	2008 Mar 27	18293908
1-(2,6-Difluoro-benzo-yl)-3-(2,3,5-tri-chloro-phen-yl)urea.	2008 Oct 11	21580966
Iridium derivatives of fluorinated aromatics by C-H activation: isolation of classical and non-classical hydrides.	2008 Oct 14	18813374
(4-Chloro-2-fluoro-phen-yl)[1-(2,6-difluoro-phen-yl)but-3-en-yl]amine.	2009 Apr 10	21583847
Synthesis and biological evaluation of salicylic acid and N-acetyl-2-carboxybenzenesulfonamide regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.	2009 Dec 15	19884005
Structural bioinformatics-based prediction of exceptional selectivity of p38 MAP kinase inhibitor PH-797804.	2009 Jul 14	19496616
The effect of perfluorination on the aromaticity of benzene and heterocyclic six-membered rings.	2009 Jun 18	19472981
1,3-Difluoro-benzene.	2009 Oct 7	21578278
(3E,5E)-1-Benzyl-3,5-bis-(2-fluoro-benzyl-idene)piperidin-4-one.	2009 Oct 7	21578277
4-[(E)-(2,4-Difluoro-phen-yl)(hydroxy-imino)meth-yl]piperidinium picrate.	2009 Sep 5	21577832
Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and fluconazole.	2010 Apr 6	20386598
Anionic N-heterocyclic carbenes with N,N'-bis(fluoroaryl) and N,N'-bis(perfluoroaryl) substituents.	2010 Dec 27	20981666
Slow magnetic relaxation in a family of trigonal pyramidal iron(II) pyrrolide complexes.	2010 Dec 29	21141856
Probing the interaction of archaeal DNA polymerases with deaminated bases using X-ray crystallography and non-hydrogen bonding isosteric base analogues.	2010 Jul 13	20527806
Intramolecular halogen stabilization of silylium ions directs gearing dynamics.	2010 Jun 16	20499871
Fluconazolium picrate.	2010 Sep 15	21587553

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:21:56 GMT 2023` Edited by `admin` on `Fri Dec 15 16:21:56 GMT 2023`
Record UNII	VO3C26WOC2
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

M-DIFLUOROBENZENE

Systematic Name

English

1,3-DIFLUOROBENZENE

Systematic Name

English

BENZENE, 1,3-DIFLUORO-

Systematic Name

English

2,4-DIFLUOROBENZENE

Systematic Name

English

1,3-BISFLUOROBENZENE

Systematic Name

English

NSC-10285

Code

English

BENZENE, M-DIFLUORO-

Systematic Name

English

Code System Code Type Description

CAS

372-18-9