O-(2-CHLORO-4-NITROPHENYL) O-ISOPROPYL ETHYLPHOSPHONOTHIOATE

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H15ClNO4PS
Molecular Weight	323.733
Optical Activity	( + / - )
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of O-(2-CHLORO-4-NITROPHENYL) O-ISOPROPYL ETHYLPHOSPHONOTHIOATE

Structure Search

SMILES

CCP(=S)(OC(C)C)OC1=C(Cl)C=C(C=C1)[N+]([O-])=O

InChI

InChIKey=QINWTFKFPMRNJP-UHFFFAOYSA-N

InChI=1S/C11H15ClNO4PS/c1-4-18(19,16-8(2)3)17-11-6-5-9(13(14)15)7-10(11)12/h5-8H,4H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C11H15ClNO4PS
Molecular Weight	323.733
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5294255

O-(2-chloro-4-nitrophenyl)-O-isopropyl ethylphosphonothioate (also known as Stauffer N-2404) is an organophosphorus larvicide, which is toxic to mammalian.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

PubMed

Title	Date	PubMed
Toxicities of certain larvicides to resistant and susceptible Aedes aegypti (L.).	1965	5294255

Patents

Sample Use Guides

In Vivo Use Guide

acute oral toxicity in rats: LD50 = 32 mg/kg

Route of Administration: Oral

In Vitro Use Guide

It was measured the toxicities to the DDT-resistant Trinidad strain of organophosphorus compounds, including Stauffer N-2404 (O-(2-CHLORO-4-NITROPHENYL) O-ISOPROPYL ETHYLPHOSPHONOTHIOATE). Stauffer N-2404 is comparable in toxicity to parathion and slightly more toxic than fenthion. The LC50 value for Stauffer N-2404 was 0.011 ppm and LC100 was 0.04 ppm.

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:25:29 GMT 2025` Edited by `admin` on `Mon Mar 31 22:25:29 GMT 2025`
Record UNII	VNH9MME03X
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

STAUFFER N-2404

Preferred Name

English

O-(2-CHLORO-4-NITROPHENYL) O-ISOPROPYL ETHYLPHOSPHONOTHIOATE

Systematic Name

English

PHOSPHONOTHIOIC ACID, ETHYL-, O-(2-CHLORO-4-NITROPHENYL) O-(1-METHYLETHYL) ESTER

Systematic Name

English

ENT-25755

Code

English

OMS-405

Code

English

ENT 25,755

Code

English

Code System Code Type Description

EPA CompTox

DTXSID2042222