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Details

Stereochemistry ACHIRAL
Molecular Formula ClO4
Molecular Weight 99.451
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge -1

SHOW SMILES / InChI
Structure of PERCHLORATE ION

SMILES

[O-]Cl(=O)(=O)=O

InChI

InChIKey=VLTRZXGMWDSKGL-UHFFFAOYSA-M
InChI=1S/ClHO4/c2-1(3,4)5/h(H,2,3,4,5)/p-1

HIDE SMILES / InChI

Molecular Formula ClHO4
Molecular Weight 100.459
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Perchloric acid is a strong acid used for complete digestions of organic material. To prevent injury, goggles or face shield, gloves, and apron must be worn. Perchloric acid must not be mixed with any other waste and should be stored separately from the other chemicals.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
PERCHLORACAP

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Application of perchloric acid technique to protozoa.
1949 Dec 16
Perchloric acid in the cytochemistry of pentose nucleic acid.
1949 Nov 4
Loss of ATP in micromolar amounts after perchloric acid treatment.
1976 Nov 5
Purification and characterization of (per)chlorate reductase from the chlorate-respiring strain GR-1.
1999 Nov
Cell necrosis and apoptosis are differentially regulated during goitre development and iodine-induced involution.
2002 Feb
The pharmacokinetics of perchlorate and its effect on the hypothalamus-pituitary-thyroid axis in the male rat.
2002 Jul 15
Functional activity of human sodium/iodide symporter in tumor cell lines.
2003 Feb
Probasin promoter (ARR(2)PB)-driven, prostate-specific expression of the human sodium iodide symporter (h-NIS) for targeted radioiodine therapy of prostate cancer.
2003 Nov 15
Human 3'-phosphoadenosine 5'-phosphosulfate synthetase (isoform 1, brain): kinetic properties of the adenosine triphosphate sulfurylase and adenosine 5'-phosphosulfate kinase domains.
2004 Apr 13
Establishment of a human hepatocellular carcinoma cell line highly expressing sodium iodide symporter for radionuclide gene therapy.
2004 Sep
A novel therapeutic strategy for medullary thyroid cancer based on radioiodine therapy following tissue-specific sodium iodide symporter gene expression.
2005 Aug
Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate.
2005 Feb 1
The BeWo choriocarcinoma cell line as a model of iodide transport by placenta.
2005 May
Development of a rat dosimetry model for bromate.
2006 Apr 17
Evaluation of gene expression endpoints in the context of a Xenopus laevis metamorphosis-based bioassay to detect thyroid hormone disruptors.
2006 Jan 5
Effects of prolonged exposure to perchlorate on thyroid and reproductive function in zebrafish.
2007 Apr
Cell-based imaging of sodium iodide symporter activity with the yellow fluorescent protein variant YFP-H148Q/I152L.
2007 Feb
[Expressions of collagen in lung of rats exposed to ammonium perchlorate].
2007 Feb
Low-dose effects of ammonium perchlorate on the hypothalamic-pituitary-thyroid axis of adult male rats pretreated with PCB126.
2007 Jun
Duox expression and related H2O2 measurement in mouse thyroid: onset in embryonic development and regulation by TSH in adult.
2007 Mar
Identification of gene expression indicators for thyroid axis disruption in a Xenopus laevis metamorphosis screening assay. Part 1. Effects on the brain.
2007 May 31
Identification of gene expression indicators for thyroid axis disruption in a Xenopus laevis metamorphosis screening assay. Part 2. Effects on the tail and hindlimb.
2007 May 31
Perchlorate and ethylenethiourea induce different histological and molecular alterations in a non-mammalian vertebrate model of thyroid goitrogenesis.
2009 Jan 27
Perchlorate transport and inhibition of the sodium iodide symporter measured with the yellow fluorescent protein variant YFP-H148Q/I152L.
2010 Mar 15
Inhibition of thyroid hormone release from cultured amphibian thyroid glands by methimazole, 6-propylthiouracil, and perchlorate.
2010 Nov
The effects of perchlorate on thyroidal gene expression are different from the effects of iodide deficiency.
2011
Biomarker expression in lung of rabbit with pulmonary fibrosis induced by ammonium perchlorate.
2011 Apr
The effects of ammonium perchlorate on thyroid homeostasis and thyroid-specific gene expression in rat.
2012 Aug
Development of an enzymatic assay to measure lactate in perchloric acid-precipitated cerebrospinal fluid.
2018 Aug
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 01:42:55 GMT 2023
Edited
by admin
on Sat Dec 16 01:42:55 GMT 2023
Record UNII
VLA4NZX2P4
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PERCHLORATE ION
Common Name English
PERCHLORATE ION(1-)
Common Name English
PERCHLORIC ACID, ION(1-)
Common Name English
PERCHLORATE
Systematic Name English
Code System Code Type Description
MESH
C494474
Created by admin on Sat Dec 16 01:42:55 GMT 2023 , Edited by admin on Sat Dec 16 01:42:55 GMT 2023
PRIMARY
FDA UNII
VLA4NZX2P4
Created by admin on Sat Dec 16 01:42:55 GMT 2023 , Edited by admin on Sat Dec 16 01:42:55 GMT 2023
PRIMARY
PUBCHEM
123351
Created by admin on Sat Dec 16 01:42:55 GMT 2023 , Edited by admin on Sat Dec 16 01:42:55 GMT 2023
PRIMARY
EPA CompTox
DTXSID6024252
Created by admin on Sat Dec 16 01:42:55 GMT 2023 , Edited by admin on Sat Dec 16 01:42:55 GMT 2023
PRIMARY
CHEBI
49706
Created by admin on Sat Dec 16 01:42:55 GMT 2023 , Edited by admin on Sat Dec 16 01:42:55 GMT 2023
PRIMARY
CAS
14797-73-0
Created by admin on Sat Dec 16 01:42:55 GMT 2023 , Edited by admin on Sat Dec 16 01:42:55 GMT 2023
PRIMARY
DRUG BANK
DB03138
Created by admin on Sat Dec 16 01:42:55 GMT 2023 , Edited by admin on Sat Dec 16 01:42:55 GMT 2023
PRIMARY
WIKIPEDIA
PERCHLORATE
Created by admin on Sat Dec 16 01:42:55 GMT 2023 , Edited by admin on Sat Dec 16 01:42:55 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY