Details
| Stereochemistry | EPIMERIC |
| Molecular Formula | C28H38O7 |
| Molecular Weight | 486.5971 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 7 / 8 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@]12CC[C@@]3(C)[C@@]([H])(C=C(C)[C@@]4(C)C(=O)C(C)C(=O)[C@@]34C(=O)OC)[C@@]1(CC[C@H](OC(C)=O)C2(C)C)C=O
InChI
InChIKey=GRBXNADBNJGZRK-GJEDHNSHSA-N
InChI=1S/C28H38O7/c1-15-13-19-25(6,28(23(33)34-8)22(32)16(2)21(31)26(15,28)7)11-9-18-24(4,5)20(35-17(3)30)10-12-27(18,19)14-29/h13-14,16,18-20H,9-12H2,1-8H3/t16?,18-,19-,20+,25+,26+,27+,28-/m1/s1
| Molecular Formula | C28H38O7 |
| Molecular Weight | 486.5971 |
| Charge | 0 |
| Count |
|
| Stereochemistry | EPIMERIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 7 / 8 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Andrastins A-C, new protein farnesyltransferase inhibitors produced by Penicillium sp. FO-3929. I. Producing strain, fermentation, isolation, and biological activities. | 1996 May |
|
| Comparison of secondary metabolite production by Penicillium crustosum strains, isolated from Arctic and other various ecological niches. | 2005 Jun 1 |
|
| Mycotoxins and other secondary metabolites produced in vitro by Penicillium paneum Frisvad and Penicillium roqueforti Thom isolated from baled grass silage in Ireland. | 2006 Nov 29 |
|
| Genetic variation among Penicillium crustosum isolates from arctic and other ecological niches. | 2007 Aug |
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| Proteolytic activity, mycotoxins and andrastin A in Penicillium roqueforti strains isolated from Cabrales, Valdeón and Bejes-Tresviso local varieties of blue-veined cheeses. | 2009 Nov 30 |
|
| Multi-mycotoxin analysis of maize silage by LC-MS/MS. | 2010 May |
|
| In vitro cytotoxicity of fungi spoiling maize silage. | 2011 Jan |
|
| Penicillium araracuarense sp. nov., Penicillium elleniae sp. nov., Penicillium penarojense sp. nov., Penicillium vanderhammenii sp. nov. and Penicillium wotroi sp. nov., isolated from leaf litter. | 2011 Jun |
|
| Atlantinone A, a Meroterpenoid Produced by Penicillium ribeum and Several Cheese Associated Penicillium Species. | 2012 Feb 23 |
|
| Mass spectrometry-based chemotaxonomic classification of Penicillium species (P. echinulatum, P. expansum, P. solitum, and P. oxalicum) and its correlation with antioxidant activity. | 2012 Sep |
|
| Occurrence of pre- and post-harvest mycotoxins and other secondary metabolites in Danish maize silage. | 2014 Jul 31 |
|
| Secondary metabolites from Penicillium corylophilum isolated from damp buildings. | 2014 Jul-Aug |
|
| Penicillium excelsum sp. nov from the Brazil Nut Tree Ecosystem in the Amazon Basin'. | 2015 |
|
| Fungal and bacterial metabolites associated with natural contamination of locally processed rice (Oryza sativa L.) in Nigeria. | 2015 |
|
| Metabolomic and Transcriptomic Comparison of Solid-State and Submerged Fermentation of Penicillium expansum KACC 40815. | 2016 |
|
| Validation and application of a liquid chromatography-tandem mass spectrometry based method for the assessment of the co-occurrence of mycotoxins in maize silages from dairy farms in NW Spain. | 2016 Dec |
|
| Cytochrome P450 for Citreohybridonol Synthesis: Oxidative Derivatization of the Andrastin Scaffold. | 2016 Jan 15 |
|
| Role of sfk1 Gene in the Filamentous Fungus Penicillium roqueforti. | 2017 |
|
| The Biosynthetic Gene Cluster for Andrastin A in Penicillium roqueforti. | 2017 |
|
| Silencing of a second dimethylallyltryptophan synthase of Penicillium roqueforti reveals a novel clavine alkaloid gene cluster. | 2017 Aug |
|
| Enniatin B and beauvericin are common in Danish cereals and show high hepatotoxicity on a high-content imaging platform. | 2017 May |
|
| Inflammation-associated gene expression in RAW 264.7 macrophages induced by toxins from fungi common on damp building materials. | 2017 Sep |
|
| The developmental regulator Pcz1 affects the production of secondary metabolites in the filamentous fungus Penicillium roqueforti. | 2018 Jul-Aug |
|
| Tyrosine Induced Metabolome Alterations of Penicillium roqueforti and Quantitation of Secondary Key Metabolites in Blue-Mold Cheese. | 2019 Aug 7 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 12:49:31 GMT 2023
by
admin
on
Sat Dec 16 12:49:31 GMT 2023
|
| Record UNII |
VL8DJU4GFD
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| Record Status |
Validated (UNII)
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| Record Version |
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DTXSID70938482
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174232-42-9
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697452
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496693
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Andrastin A
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VL8DJU4GFD
Created by
admin on Sat Dec 16 12:49:31 GMT 2023 , Edited by admin on Sat Dec 16 12:49:31 GMT 2023
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PRIMARY |