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Details

Stereochemistry ACHIRAL
Molecular Formula C17H11Cl3NO4S.Na
Molecular Weight 454.687
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ENOLICAM SODIUM ANHYDROUS

SMILES

[Na+].[O-]C1=C(CCS(=O)(=O)C2=C1C=C(Cl)C=C2)C(=O)NC3=CC=C(Cl)C(Cl)=C3

InChI

InChIKey=DBAQZKACATZPLT-UHFFFAOYSA-M
InChI=1S/C17H12Cl3NO4S.Na/c18-9-1-4-15-12(7-9)16(22)11(5-6-26(15,24)25)17(23)21-10-2-3-13(19)14(20)8-10;/h1-4,7-8,22H,5-6H2,(H,21,23);/q;+1/p-1

HIDE SMILES / InChI
Molecular Formula C17H11Cl3NO4S
Molecular Weight 431.698
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Enolicam (CGS 5391B) is a non-steroidal anti-inflammatory drug with combined cyclooxygenase and lipoxygenase inhibitory activity. It is able to trap oxygen radicals. Enolicam was effective in animal models of traumatic shock and osteoarthritis.

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
A new model of osteoarthritis in rabbits. II. Evaluation of anti-osteoarthritic effects of selected antirheumatic drugs administered systemically.
1983 Sep
Diclofenac and enolicam as ocular anti-inflammatory drugs in rabbit corneal wound model.
1986 Spring
The amplified chemiluminescence test to characterize antirheumatic drugs as oxygen radical scavengers.
1987 Apr 1
Amiodarone causes acute oxidant lung injury in ventilated and perfused rabbit lungs.
1988 Jul
Substance Class Chemical
Created
by admin
on Sat Dec 16 04:51:33 GMT 2023
Edited
by admin
on Sat Dec 16 04:51:33 GMT 2023
Record UNII
VKD61J0J01
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ENOLICAM SODIUM ANHYDROUS
Common Name English
CGS-5391B
Code English
3',4',7-TRICHLORO-2,3-DIHYDRO-5-HYDROXY-1-BENZOTHIEPIN-4-CARBOXANILIDE 1,1-DIOXIDE, MONOSODIUM SALT
Common Name English
1-BENZOTHIEPIN-4-CARBOXAMIDE, 7-CHLORO-N-(3,4-DICHLOROPHENYL)-2,3-DIHYDRO-5-HYDROXY-, 1,1-DIOXIDE, MONOSODIUM SALT
Common Name English
1-BENZOTHIEPIN-4-CARBOXAMIDE, 7-CHLORO-N-(3,4-DICHLOROPHENYL)-2,3-DIHYDRO-5-HYDROXY-, 1,1-DIOXIDE, SODIUM SALT (1:1)
Common Name English
CGS 5391B
Code English
Code System Code Type Description
FDA UNII
VKD61J0J01
Created by admin on Sat Dec 16 04:51:33 GMT 2023 , Edited by admin on Sat Dec 16 04:51:33 GMT 2023
PRIMARY
PUBCHEM
23677876
Created by admin on Sat Dec 16 04:51:33 GMT 2023 , Edited by admin on Sat Dec 16 04:51:33 GMT 2023
PRIMARY
CAS
59756-39-7
Created by admin on Sat Dec 16 04:51:33 GMT 2023 , Edited by admin on Sat Dec 16 04:51:33 GMT 2023
PRIMARY
Related Record Type Details
Structure of ENOLICAM SODIUM
SOLVATE->ANHYDROUS
Related Record Type Details
Structure of ENOLICAM
ACTIVE MOIETY
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