LONIGUTAMAB UGODOTIN

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NCATS

Approval Year

Substance Class	Protein
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1
Sequence Type	COMPLETE
Record UNII	VJ9X8A8CJ5
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LONIGUTAMAB UGODOTIN

Official Name

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS IGF1R (INSULIN LIKE GROWTH FACTOR 1 RECEPTOR, IGF1-R, IGF-1R, CD221)), HUMANIZED MONOCLONAL ANTIBODY CONJUGATED TO A DOLASTATIN DERIVATIVE (UGODOTIN GROUPS)

Common Name

English

IMMUNOGLOBULIN G1 (DE-C-TERMINAL-LYSINE), ANTI-(HUMAN INSULIN-LIKE GROWTH FACTOR I RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL HZ-208F2-4 .GAMMA.1-CHAIN), COMPLEX WITH HUMAN-MUS MUSCULUS MONOCLONAL HZ-208F2-4 .KAPPA.-CHAIN, DIMER, TETRAKIS(THIOETHER) WITH N

Common Name

English

lonigutamab ugodotin [INN]

Common Name

English

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Code System

Code

Type

Description

INN

11640

PRIMARY

INN

FDA UNII

VJ9X8A8CJ5

PRIMARY

NCI_THESAURUS

C179101

PRIMARY

CAS

2363754-30-5

PRIMARY

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Subunit 0

Subunit 1

Subunit 2

Subunit 3

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From	To
1_22	1_96
2_22	2_96
2_147	2_203
2_264	2_324
1_147	1_203

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Type

Details


					56GN9PT35D

PARENT -> CONJUGATE

Amount:


					1Z1AI9IW5L

MONOMETHYL AURISTATIN F

CONJUGATE COMPONENT->CONJUGATE

Amount:


					DK7PL4F3TT

INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR

TARGET->LIGAND

Amount:

Showing 1 to 3 of 3 entries

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Related Record

Type

Details


					VJ9X8A8CJ5

LONIGUTAMAB UGODOTIN

ACTIVE MOIETY

Amount:

Showing 1 to 1 of 1 entries

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL	ESTIMATED 146000 Da (average)
Molecular Formula	CHEMICAL	ESTIMATED C6468H10028O2002N1724S50

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