BIALAMICOL HYDROCHLORIDE

US Previously Marketed

First approved in 1956

Details

Stereochemistry	ACHIRAL
Molecular Formula	C28H40N2O2.2ClH
Molecular Weight	509.551
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.Cl.CCN(CC)CC1=CC(=CC(CC=C)=C1O)C2=CC(CN(CC)CC)=C(O)C(CC=C)=C2

InChI

InChIKey=SLKLQAMVBKKGMQ-UHFFFAOYSA-N

InChI=1S/C28H40N2O2.2ClH/c1-7-13-21-15-23(17-25(27(21)31)19-29(9-3)10-4)24-16-22(14-8-2)28(32)26(18-24)20-30(11-5)12-6;;/h7-8,15-18,31-32H,1-2,9-14,19-20H2,3-6H3;2*1H

HIDE SMILES / InChI

Molecular Formula	C28H40N2O2
Molecular Weight	436.6294
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.drugfuture.com/chemdata/bialamicol.html | https://www.ncbi.nlm.nih.gov/pubmed/13462856

BIALAMICOL is a hydroxybiphenyl antiprotozoal used for the treatment of acute and chronic amoebiasis.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
amoebiasis 2 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14365670	Curative		Not Provided 504	Camoform Approved Use Unknown

Sourcing

Vendor/Aggregator	ID	URL
AAA Chemistry	AR-1I1662
ABI Chem	AC1L1UX2
ABI Chem	AC1Q79KL
Ambinter	Amb22546991	http://www.ambinter.com/reference/22546991
BOC Sciences	3624-96-2
BOC Sciences	493-75-4
ChemMol	99092226	http://www.chemmol.com/chemmol/99092226.html
Chemieliva Pharmaceutical Co., Ltd	PBCM1316555
Compound Cloud	10304
Compound Cloud	11954305
MolMall	102129
Smolecule	S592189	https://www.smolecule.com/products/s592189
THE BioTek	bt-407000	https://www.thebiotek.com/product/others/bt-407000
Yick-Vic Chemicals & Pharmaceuticals (HK) Ltd.	PH-0356
ZINC	ZINC000004215006	http://zinc15.docking.org/substances/ZINC000004215006
eMolecules	259859409
eMolecules	93968060
mcule	MCULE-4107624945

PubMed

Title	Date	PubMed
The treatment of acute and chronic amoebiasis; camoform (PAA-701).	1955 Feb	14365670
Treatment of amebiasis with camoform.	1957 Oct 19	13462856
ANTIAMEBIC AGENTS. VI. ANALOGS OF BIALAMICOL AND RELATED QUINOLINOLS.	1963 Jan	14174042

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:03:47 GMT 2023` Edited by `admin` on `Fri Dec 15 15:03:47 GMT 2023`
Record UNII	VIQ3X36S8C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BIALAMICOL HYDROCHLORIDE

Official Name

English

(1,1'-BIPHENYL)-4,4'-DIOL, 3,3'-BIS((DIETHYLAMINO)METHYL)-5,5'-DI-2-PROPENYL-, DIHYDROCHLORIDE

Common Name

English

PAA-701

Code

English

BIALAMICOL HCL

Common Name

English

NSC-6386

Code

English

BIALAMICOL HYDROCHLORIDE [USAN]

Common Name

English

CI-301

Code

English

Bialamicol hydrochloride [WHO-DD]

Common Name

English

5,5'-DIALLYL-.ALPHA.,.ALPHA.'-BIS(DIETHYLAMINO)-M,M'-BITOLYL-4,4'-DIOL DIHYDROCHLORIDE

Common Name

English

CAM-807

Code

English

BIALAMICOL DIHYDROCHLORIDE [MI]

Common Name

English

Code System Code Type Description

SMS_ID

100000085025