U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 16:08:11 GMT 2023
Edited
by admin
on Sat Dec 16 16:08:11 GMT 2023
Source Materials Class ORGANISM
Source Materials Type VIRUS
Source Materials State LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family Retroviridae
Organism Genus Lentivirus
Organism Species human immunodeficiency virus 1
Infraspecific Type SUBSTRAIN
Infraspecific Name LENTIVIRAL VECTOR (PLBP100 HALD)-MND-ABCD1
Part WHOLE
Record UNII
VI2NBA6B8C
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ELIVALDOGENE TAVALENTIVEC
INN  
USAN   INN  
Official Name English
LENTI-D DRUG PRODUCT
Code English
LENTI-D
Code English
elivaldogene tavalentivec [INN]
Common Name English
DNA (LENTIVIRAL VECTOR CLONE LENTI-D HUMAN X-LINKED ADRENOLEUKODYSTROPHY ABCD1 GENE CDNA-SPECIFYING)
Common Name English
A VSV-G*-PSEUDOTYPED SELF-INACTIVATING HIV-1-DERIVED LENTIVIRAL VECTOR (PLBP100 HALD) ENCODING HUMAN ADRENOLEUKODYSTROPHY (ALD) PROTEIN (ABCD1 GENE) UNDER THE CONTROL OF A MODIFIED MYELOPROLIFERATIVE SARCOMA VIRUS PROMOTER
Systematic Name English
ELIVALDOGENE TAVALENTIVEC [USAN]
Common Name English
Code System Code Type Description
FDA UNII
VI2NBA6B8C
Created by admin on Sat Dec 16 16:08:11 GMT 2023 , Edited by admin on Sat Dec 16 16:08:11 GMT 2023
PRIMARY
CAS
1905397-73-0
Created by admin on Sat Dec 16 16:08:11 GMT 2023 , Edited by admin on Sat Dec 16 16:08:11 GMT 2023
PRIMARY
USAN
EF-145
Created by admin on Sat Dec 16 16:08:11 GMT 2023 , Edited by admin on Sat Dec 16 16:08:11 GMT 2023
PRIMARY
NCI_THESAURUS
C169938
Created by admin on Sat Dec 16 16:08:11 GMT 2023 , Edited by admin on Sat Dec 16 16:08:11 GMT 2023
PRIMARY
INN
10074
Created by admin on Sat Dec 16 16:08:11 GMT 2023 , Edited by admin on Sat Dec 16 16:08:11 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
GENE_EXPRESSION VECTOR ELIVALDOGENE TAVALENTIVEC TRANSGENE INSERT FAO1H5M18V