Approval Year
| Substance Class |
Nucleic Acid
Created
by
admin
on
Edited
Sat Dec 16 15:08:48 UTC 2023
by
admin
on
Sat Dec 16 15:08:48 UTC 2023
|
| Nucleic Acid Type | siRNA |
| Nucleic Acid Subtype | |
| Sequence Type | COMPLETE |
| Record UNII |
VHB1T5I5S1
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Official Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
10736
Created by
admin on Sat Dec 16 15:08:48 UTC 2023 , Edited by admin on Sat Dec 16 15:08:48 UTC 2023
|
PRIMARY | |||
|
VHB1T5I5S1
Created by
admin on Sat Dec 16 15:08:48 UTC 2023 , Edited by admin on Sat Dec 16 15:08:48 UTC 2023
|
PRIMARY | |||
|
1974402-87-3
Created by
admin on Sat Dec 16 15:08:48 UTC 2023 , Edited by admin on Sat Dec 16 15:08:48 UTC 2023
|
PRIMARY | |||
|
C169969
Created by
admin on Sat Dec 16 15:08:48 UTC 2023 , Edited by admin on Sat Dec 16 15:08:48 UTC 2023
|
PRIMARY |
| Sugar | Site Range | Site Count |
|---|---|---|
| Deoxyribose (DNA) | 1_1-1_32;2_1-2_32 | 64 / 64 |
| Linkage | Site Range | Site Count |
|---|---|---|
| Phosporothioate | 1_1-1_3;2_30-2_32 | 6 / 62 |
| Phosphate | 1_4-1_31;2_1-2_28 | 56 / 62 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
ACTIVE MOIETY |
DNA repair pathway inhibitor
|
Structural Modifications
| Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
|---|---|---|---|---|---|---|
| LINK | [1_32] [2_1] | SITE_SPECIFIC | ETIDALIGIDE ADENINE(32) 3'-MODIFICATION | 64G05FP5JN | ||
| AMINO_ACID_SUBSTITUTION | [1_1] | ETIDALIGIDE 5'-STEROID-LINKED | A65A4CGS6P |