| Stereochemistry | ABSOLUTE |
| Molecular Formula | C10H14N5O6P |
| Molecular Weight | 331.2218 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC1=NC=NC2=C1N=CN2[C@H]3C[C@H](O)[C@@H](COP(O)(O)=O)O3
InChI
InChIKey=KHWCHTKSEGGWEX-RRKCRQDMSA-N
InChI=1S/C10H14N5O6P/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(21-7)2-20-22(17,18)19/h3-7,16H,1-2H2,(H2,11,12,13)(H2,17,18,19)/t5-,6+,7+/m0/s1
| Molecular Formula | C10H14N5O6P |
| Molecular Weight | 331.2218 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Originator
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
PubMed
Patents
Sample Use Guides
Enzymatic parameters for dAMP phosphorylation by adenylate kinases were measured using spectroscopic Pyruvate kinase/lactate dehydrogenase coupled assay to allow measuring ADP formation. The assay mix contained 50 mM Tris–HCl pH 7.4, 5 mM MgCl2, 1 mM ATP, 0.2 mM NADH, 10 mM DTT, 1 mM phosphoenolpyruvate and auxiliary enzymes: pyruvate kinase (4 Units) and lactate dehydrogenase (4 Units).