Details
Stereochemistry | ACHIRAL |
Molecular Formula | C19H10N2O |
Molecular Weight | 282.2955 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
O=C1C2=C(C=CC=C2)C3=C1C4=CC=C5C=CC=CC5=C4N=N3
InChI
InChIKey=NCXXMBGUOLIVCB-UHFFFAOYSA-N
InChI=1S/C19H10N2O/c22-19-14-8-4-3-7-13(14)18-16(19)15-10-9-11-5-1-2-6-12(11)17(15)20-21-18/h1-10H
Molecular Formula | C19H10N2O |
Molecular Weight | 282.2955 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 10:08:01 GMT 2023
by
admin
on
Sat Dec 16 10:08:01 GMT 2023
|
Record UNII |
VFR3BK96HV
|
Record Status |
Validated (UNII)
|
Record Version |
|
-
Download
Name | Type | Language | ||
---|---|---|---|---|
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English |
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
|
VFR3BK96HV
Created by
admin on Sat Dec 16 10:08:01 GMT 2023 , Edited by admin on Sat Dec 16 10:08:01 GMT 2023
|
PRIMARY | |||
|
166760-48-1
Created by
admin on Sat Dec 16 10:08:01 GMT 2023 , Edited by admin on Sat Dec 16 10:08:01 GMT 2023
|
PRIMARY | |||
|
10423885
Created by
admin on Sat Dec 16 10:08:01 GMT 2023 , Edited by admin on Sat Dec 16 10:08:01 GMT 2023
|
PRIMARY |
Related Record | Type | Details | ||
---|---|---|---|---|
|
PARENT -> DERIVATIVE |
Analogue of compound KLB-1 and it?s ability to inhibit growth of PhIP-resistant clones. Molecular weight = 282.30; IC50 PhIP = 40.0 umol/L ; Fold difference = 17.0.
Screening used a derivative of the human colorectal cancer cell line, HCT116, that harbors an additional copy of chromosome 3 to correct for mutL homologue 1 deficiency and microsatellite instability.
|