IPROHEPTINE HYDROCHLORIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H25N.ClH
Molecular Weight	207.784
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CC(C)CCCC(C)NC(C)C

InChI

InChIKey=QYEORIIWGAAORG-UHFFFAOYSA-N

InChI=1S/C11H25N.ClH/c1-9(2)7-6-8-11(5)12-10(3)4;/h9-12H,6-8H2,1-5H3;1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C11H25N
Molecular Weight	171.3229
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: http://iccb.med.harvard.edu/files/iccb/files/msdisc1_knownbioactivelibraries_activities_website_09092015.pdf | http://www.google.ch/patents/WO2005094832A1

Iproheptine (Metron, Susat) is a vasoconstrictor, antihistamine, nasal decongestant marketed in Japan.

CNS Activity

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Histamine H1 receptor 315 Target ID: CHEMBL231 Sources: http://www.google.ch/patents/WO2005094832A1 \| http://www.chemicalland21.com/info/ANTIHISTAMINES.htm	Antagonist 2778

Conditions

Condition	Modality	Targets	Highest Phase	Product
Nasal congestion 26 Sources: http://iccb.med.harvard.edu/files/iccb/files/msdisc1_knownbioactivelibraries_activities_website_09092015.pdf http://www.google.ch/patents/WO2005094832A1	Primary		Approved 8429	METRON Approved Use Vasoconstrictor, antihistamine, nasal decongestant

Patents

Sample Use Guides

In Vivo Use Guide

Maximum daily dose - 150mg

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:37:05 GMT 2023` Edited by `admin` on `Fri Dec 15 17:37:05 GMT 2023`
Record UNII	VFP5V1ZZMK
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

IPROHEPTINE HYDROCHLORIDE

Common Name

English

Iproheptine hydrochloride [WHO-DD]

Common Name

English

N-ISOPROPYL-6-METHYL-2-HEPTYLAMINE HYDROCHLORIDE

Systematic Name

English

6-METHYL-N-(1-METHYLETHYL)-2-HEPTANAMINE HYDROCHLORIDE

Systematic Name

English

2-HEPTANAMINE, 6-METHYL-N-(1-METHYLETHYL)-, HYDROCHLORIDE (1:1)

Systematic Name

English

IPROHEPTINE HYDROCHLORIDE [JAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29578