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Details

Stereochemistry RACEMIC
Molecular Formula C11H25N.ClH
Molecular Weight 207.784
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of IPROHEPTINE HYDROCHLORIDE

SMILES

Cl.CC(C)CCCC(C)NC(C)C

InChI

InChIKey=QYEORIIWGAAORG-UHFFFAOYSA-N
InChI=1S/C11H25N.ClH/c1-9(2)7-6-8-11(5)12-10(3)4;/h9-12H,6-8H2,1-5H3;1H

HIDE SMILES / InChI

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C11H25N
Molecular Weight 171.3229
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Iproheptine (Metron, Susat) is a vasoconstrictor, antihistamine, nasal decongestant marketed in Japan.

CNS Activity

Curator's Comment: First-generation antihistamine - can cause side effect of sedation.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
METRON

Approved Use

Vasoconstrictor, antihistamine, nasal decongestant

Sample Use Guides

In Vivo Use Guide
Curator's Comment: A daily combination dosage of iproheptine hydrochloride for an adult is usually between 10 and 225 mg, preferably between 20 and 200 mg, more preferably between 30 and 150 mg. http://www.google.ch/patents/WO2005094832A1
Maximum daily dose - 150mg
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 17:37:05 GMT 2023
Edited
by admin
on Fri Dec 15 17:37:05 GMT 2023
Record UNII
VFP5V1ZZMK
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IPROHEPTINE HYDROCHLORIDE
JAN   WHO-DD  
Common Name English
Iproheptine hydrochloride [WHO-DD]
Common Name English
N-ISOPROPYL-6-METHYL-2-HEPTYLAMINE HYDROCHLORIDE
Systematic Name English
6-METHYL-N-(1-METHYLETHYL)-2-HEPTANAMINE HYDROCHLORIDE
Systematic Name English
2-HEPTANAMINE, 6-METHYL-N-(1-METHYLETHYL)-, HYDROCHLORIDE (1:1)
Systematic Name English
IPROHEPTINE HYDROCHLORIDE [JAN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29578
Created by admin on Fri Dec 15 17:37:05 GMT 2023 , Edited by admin on Fri Dec 15 17:37:05 GMT 2023
Code System Code Type Description
CAS
4013-92-7
Created by admin on Fri Dec 15 17:37:05 GMT 2023 , Edited by admin on Fri Dec 15 17:37:05 GMT 2023
PRIMARY
EPA CompTox
DTXSID30960567
Created by admin on Fri Dec 15 17:37:05 GMT 2023 , Edited by admin on Fri Dec 15 17:37:05 GMT 2023
PRIMARY
NCI_THESAURUS
C97701
Created by admin on Fri Dec 15 17:37:05 GMT 2023 , Edited by admin on Fri Dec 15 17:37:05 GMT 2023
PRIMARY
SMS_ID
100000086453
Created by admin on Fri Dec 15 17:37:05 GMT 2023 , Edited by admin on Fri Dec 15 17:37:05 GMT 2023
PRIMARY
FDA UNII
VFP5V1ZZMK
Created by admin on Fri Dec 15 17:37:05 GMT 2023 , Edited by admin on Fri Dec 15 17:37:05 GMT 2023
PRIMARY
ChEMBL
CHEMBL2103925
Created by admin on Fri Dec 15 17:37:05 GMT 2023 , Edited by admin on Fri Dec 15 17:37:05 GMT 2023
PRIMARY
EVMPD
SUB02770MIG
Created by admin on Fri Dec 15 17:37:05 GMT 2023 , Edited by admin on Fri Dec 15 17:37:05 GMT 2023
PRIMARY
PUBCHEM
19916
Created by admin on Fri Dec 15 17:37:05 GMT 2023 , Edited by admin on Fri Dec 15 17:37:05 GMT 2023
PRIMARY
Related Record Type Details
ENANTIOMER -> RACEMATE
PARENT -> SALT/SOLVATE
ENANTIOMER -> RACEMATE
Related Record Type Details
ACTIVE MOIETY