TRICLOBISONIUM CHLORIDE

US Previously Marketed

First approved in 1959

Details

Stereochemistry	MIXED
Molecular Formula	C36H74N2.2Cl
Molecular Weight	605.892
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Cl-].[Cl-].CC(CCC1C(C)CCCC1(C)C)[N+](C)(C)CCCCCC[N+](C)(C)C(C)CCC2C(C)CCCC2(C)C

InChI

InChIKey=JMTNOKRGERWNME-UHFFFAOYSA-L

InChI=1S/C36H74N2.2ClH/c1-29-19-17-25-35(5,6)33(29)23-21-31(3)37(9,10)27-15-13-14-16-28-38(11,12)32(4)22-24-34-30(2)20-18-26-36(34,7)8;;/h29-34H,13-28H2,1-12H3;2*1H/q+2;;/p-2

HIDE SMILES / InChI

Molecular Formula	C36H74N2
Molecular Weight	534.9862
Charge	2
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13819270 | https://www.ncbi.nlm.nih.gov/pubmed/13800549

TRICLOBISONIUM (as a chloride salt) is an antibacterial agent used for the treatment and/or prevention of local infections.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Trichomonas vaginalis 2 Sources: https://www.ncbi.nlm.nih.gov/pubmed/13726669	Primary		Approved 8429	Triburon Approved Use Unknown

Sourcing

Vendor/Aggregator	ID	URL
ABI Chem	AC1L1MX4
Alfa Chemistry	ACM79903
ZINC	ZINC000003875528	http://zinc15.docking.org/substances/ZINC000003875528
ZINC	ZINC000003875529	http://zinc15.docking.org/substances/ZINC000003875529
ZINC	ZINC000003875530	http://zinc15.docking.org/substances/ZINC000003875530
ZINC	ZINC000003875531	http://zinc15.docking.org/substances/ZINC000003875531
eMolecules	260195778

PubMed

Title	Date	PubMed
Local application of triclobisonium chloride in the treatment of pyogenic dermatoses.	1958-1959	13637717
Triclobisonium chloride (triburon), an antimicrobial agent with local activity in living host tissues.	1959 May	24545208
Clinical studies of the effectiveness of a new topical antimicrobial, triclobisonium chloride.	1959 Sep 1	13819270
Trichomonas vaginalis. A clinical evaluation of triclobisonium chloride vaginal cream (Triburon).	1960 Dec	13726669

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:02:06 GMT 2023` Edited by `admin` on `Fri Dec 15 16:02:06 GMT 2023`
Record UNII	VF26809LZJ
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TRICLOBISONIUM CHLORIDE

Official Name

English

TRICLOBISONIUM CHLORIDE [MI]

Common Name

English

HEXAMETHYLENEBIS(DIMETHYL(1-METHYL-3-(2,2,6-TRIMETHYLCYCLOHEXYL)PROPYL)AMMONIUM) DICHLORIDE

Systematic Name

English

triclobisonium chloride [INN]

Common Name

English

Triclobisonium chloride [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C28394