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Details

Stereochemistry ACHIRAL
Molecular Formula C5H13N3
Molecular Weight 115.1768
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1,1,3,3-TETRAMETHYLGUANIDINE

SMILES

CN(C)C(=N)N(C)C

InChI

InChIKey=KYVBNYUBXIEUFW-UHFFFAOYSA-N
InChI=1S/C5H13N3/c1-7(2)5(6)8(3)4/h6H,1-4H3

HIDE SMILES / InChI

Molecular Formula C5H13N3
Molecular Weight 115.1768
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
X-ray crystal structure, Raman spectroscopy, and Ab initio density functional theory calculations on 1,1,3,3-tetramethylguanidinium bromide.
2010-12-23
The nature of protic ionic liquids in the gas phase revisited: Fourier transform ion cyclotron resonance mass spectrometry study of 1,1,3,3-tetramethylguanidinium chloride.
2010-07-15
tert-Butyl 4-(2-diazo-acet-yl)piperazine-1-carboxyl-ate.
2010-05-08
HABA-based ionic liquid matrices for UV-MALDI-MS analysis of heparin and heparan sulfate oligosaccharides.
2010-02
1,1,3,3-Tetramethylguanidine solvated lanthanide aryloxides: pre-catalysts for intramolecular hydroalkoxylation.
2009-12-21
One-step synthesis and bioassay of N-phosphoramidophosphonates.
2009-12
Use of a novel ionic liquid matrix for MALDI-MS analysis of glycopeptides and glycans out of total tryptic digests.
2009-11
Structurally characterized 1,1,3,3-tetramethylguanidine solvated magnesium aryloxide complexes: [Mg(mu-OEt)(DBP)(H-TMG)]2, [Mg(mu-OBc)(DBP)(H-TMG)]2, [Mg(mu-TMBA)(DBP)(H-TMG)]2, [Mg(mu-DPP)(DBP)(H-TMG)]2, [Mg(BMP)2(H-TMG)2], [Mg(O-2,6-Ph2C6H3)2 (H-TMG)2].
2009-04-06
Synthetic applications of polystyrene-supported 1,1,3,3-tetramethylguanidine.
2008-12
Formation of an ion-pair molecule with a single NH(+)...Cl(-) hydrogen bond: Raman spectra of 1,1,3,3-tetramethylguanidinium chloride in the solid state, in solution, and in the vapor phase.
2008-09-18
The synthesis of 17-alkoxycarbonyl- and 17-carboxamido-13alpha-estra-1,3,5(10),16-tetraene derivatives via palladium-catalyzed carbonylation reactions.
2008-07
The synthesis of 13alpha-androsta-5,16-diene derivatives with carboxylic acid, ester and carboxamido functionalities at position-17 via palladium-catalyzed carbonylation.
2008-06-25
Stable analogs of the uranyl ion containing 1,1,3,3-tetramethylguanidine.
2007-11-07
Facile synthesis of 11-carboxamido-androst-4,9(11)-dienes via palladium-catalyzed aminocarbonylation.
2007-07
Pt(II)-mediated nitrile-tetramethylguanidine coupling as a key step for a novel synthesis of 1,6-dihydro-1,3,5-dihydrotriazines.
2007-03-05
Structural and theoretical investigation of 2-iminoimidazolines--carbene analogues of iminophosphoranes.
2007-02-07
Similarities and differences between organic cation inhibition of the Na,K-ATPase and PMCA.
2006-11-07
Facile synthesis of 12-carboxamido-11-spirostenes via palladium-catalyzed carbonylation reactions.
2006-10
New force field for molecular simulation of guanidinium-based ionic liquids.
2006-06-22
[Study on the vibrational spectra of two nitrobenzoyl substituted guanidines].
2006-04
Microwave-assisted synthesis of pt nanocrystals and deposition on carbon nanotubes in ionic liquids.
2006-01
Guanidinophosphazenes: design, synthesis, and basicity in THF and in the gas phase.
2005-12-21
Practical synthesis of the new carbapenem antibiotic ertapenem sodium.
2005-09-16
Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity.
2005-09
A new, efficient method for direct alpha-alkenylation of beta-dicarbonyl compounds and phenols using alkenyltriarylbismuthonium salts.
2004-08-06
Recommended methods of fatty acid methylester preparation for conjugated dienes and trienes in food and biological samples.
2004-04
pH directly regulates epidermal permeability barrier homeostasis, and stratum corneum integrity/cohesion.
2003-08
A novel and convenient chemoselective deprotection method for both silyl and acetyl groups on acidic hydroxyl groups such as phenol and carboxylic acid by using a nitrogen organic base, 1,1,3,3-tetramethylguanidine.
2003-01-23
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 22:42:23 GMT 2025
Edited
by admin
on Mon Mar 31 22:42:23 GMT 2025
Record UNII
VEZ101E7ZU
Record Status Validated (UNII)
Record Version
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Name Type Language
1,1,3,3-TETRAMETHYLGUANIDINE
MI  
Systematic Name English
NSC-148309
Preferred Name English
N,N,N,N-TETRAMETHYLGUANIDINE
Systematic Name English
1,1,3,3-TETRAMETHYLGUANIDINE [MI]
Common Name English
GUANIDINE, N,N,N',N'-TETRAMETHYL-
Systematic Name English
Code System Code Type Description
ECHA (EC/EINECS)
201-302-7
Created by admin on Mon Mar 31 22:42:23 GMT 2025 , Edited by admin on Mon Mar 31 22:42:23 GMT 2025
PRIMARY
MERCK INDEX
m10645
Created by admin on Mon Mar 31 22:42:23 GMT 2025 , Edited by admin on Mon Mar 31 22:42:23 GMT 2025
PRIMARY Merck Index
WIKIPEDIA
1,1,3,3-Tetramethylguanidine
Created by admin on Mon Mar 31 22:42:23 GMT 2025 , Edited by admin on Mon Mar 31 22:42:23 GMT 2025
PRIMARY
CAS
80-70-6
Created by admin on Mon Mar 31 22:42:23 GMT 2025 , Edited by admin on Mon Mar 31 22:42:23 GMT 2025
PRIMARY
NSC
148309
Created by admin on Mon Mar 31 22:42:23 GMT 2025 , Edited by admin on Mon Mar 31 22:42:23 GMT 2025
PRIMARY
EPA CompTox
DTXSID2058835
Created by admin on Mon Mar 31 22:42:23 GMT 2025 , Edited by admin on Mon Mar 31 22:42:23 GMT 2025
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PUBCHEM
66460
Created by admin on Mon Mar 31 22:42:23 GMT 2025 , Edited by admin on Mon Mar 31 22:42:23 GMT 2025
PRIMARY
FDA UNII
VEZ101E7ZU
Created by admin on Mon Mar 31 22:42:23 GMT 2025 , Edited by admin on Mon Mar 31 22:42:23 GMT 2025
PRIMARY