U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Wed Apr 02 09:22:50 GMT 2025
Edited
by admin
on Wed Apr 02 09:22:50 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
VD026R6TCI
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IMMUNOGLOBULIN G1, ANTI-(HUMAN ROOF PLATE-SPECIFIC SPONDIN R-SPONDIN-3) (HUMAN-MUS MUSCULUS MONOCLONAL OMP-131R10 HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL OMP-131R10 .KAPPA.-CHAIN, DIMER
Preferred Name English
ROSMANTUZUMAB
INN   WHO-DD  
INN  
Official Name English
Rosmantuzumab [WHO-DD]
Common Name English
OMP131R10
Code English
ROSMANTUZUMAB [USAN]
Common Name English
OMP-131R10
Code English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS RSPO3 (RSPONDIN 3, THROMBOSPONDIN TYPE I (TSP1) DOMAIN CONTAINING PROTEIN 2, THSD2)), HUMANIZED MONOCLONAL ANTIBODY GAMMA1 HEAVY CHAIN (1-447) (HUMANIZED VH (HOMO SAPIENS IGHV1-46*01 (84.50%) -(IGHD)-IGHJ4*01)
Common Name English
rosmantuzumab [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C20401
Created by admin on Wed Apr 02 09:22:50 GMT 2025 , Edited by admin on Wed Apr 02 09:22:50 GMT 2025
Code System Code Type Description
SMS_ID
100000174669
Created by admin on Wed Apr 02 09:22:50 GMT 2025 , Edited by admin on Wed Apr 02 09:22:50 GMT 2025
PRIMARY
CAS
1684393-04-1
Created by admin on Wed Apr 02 09:22:50 GMT 2025 , Edited by admin on Wed Apr 02 09:22:50 GMT 2025
PRIMARY
NCI_THESAURUS
C122921
Created by admin on Wed Apr 02 09:22:50 GMT 2025 , Edited by admin on Wed Apr 02 09:22:50 GMT 2025
PRIMARY
WIKIPEDIA
Rosmantuzumab
Created by admin on Wed Apr 02 09:22:50 GMT 2025 , Edited by admin on Wed Apr 02 09:22:50 GMT 2025
PRIMARY
INN
10415
Created by admin on Wed Apr 02 09:22:50 GMT 2025 , Edited by admin on Wed Apr 02 09:22:50 GMT 2025
PRIMARY
FDA UNII
VD026R6TCI
Created by admin on Wed Apr 02 09:22:50 GMT 2025 , Edited by admin on Wed Apr 02 09:22:50 GMT 2025
PRIMARY
USAN
EF-57
Created by admin on Wed Apr 02 09:22:50 GMT 2025 , Edited by admin on Wed Apr 02 09:22:50 GMT 2025
PRIMARY
From To
1_22 1_96
1_144 1_200
1_261 1_321
1_367 1_425
2_22 2_96
2_144 2_200
2_261 2_321
2_367 2_425
3_23 3_92
3_138 3_198
4_23 4_92
4_138 4_198
1_220 3_218
2_220 4_218
1_226 2_226
1_229 2_229
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_297
N 2_297
Related Record Type Details
R-SPONDIN-3
TARGET -> INHIBITOR
Related Record Type Details
ROSMANTUZUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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