| Stereochemistry | RACEMIC |
| Molecular Formula | C11H17O4PS2 |
| Molecular Weight | 308.354 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCOP(=S)(OCC)OC1=CC=C(C=C1)[S+](C)[O-]
InChI
InChIKey=XDNBJTQLKCIJBV-UHFFFAOYSA-N
InChI=1S/C11H17O4PS2/c1-4-13-16(17,14-5-2)15-10-6-8-11(9-7-10)18(3)12/h6-9H,4-5H2,1-3H3
| Molecular Formula | C11H17O4PS2 |
| Molecular Weight | 308.354 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Fensulfothion is an organophosphate insecticide/nematicide. Fensulfothion is highly toxic to man and other non-target terrestrial and aquatic organisms from acute oral and dermal routes of exposure. Fensulfothion is registered for use as preplant or at-planting soil application to tobacco and various fruits and vegetables. Postplant topical applications are permitted in addition to the at-planting application on corn, peanuts, and rutabagas. Topical application is also permitted on commercial and ornamental turf. Fensulfothion is an organophosphate insecticide/nematicide that kills primarily by contact action, but also provides some systemic control of insects attacking the foliage of treated plants. The mode of action is by phosphorylating the acetylcholinesterase enzyme of tissues, allowing accumulation of acetylcholine at nerve junctions, with subsequent blocking effects upon the central nervous system.
CNS Activity
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
PubMed
Patents
Sample Use Guides
Fensulfothion is used against soil nematodes (free living, root knot and cyst forming nematodes) and a broad spectrum of soil borne insects in field crops, vegetables and fruit. It is also used against nematodes in turf grasses, in flowers and in ornamentals. Fensulfothion is highly toxic to man and other non-target terrestrial and aquatic organisms from acute oral and dermal routes of exposure.
Route of Administration:
Unknown
The effect of fensulfothion at four concentrations (1, 5, 25, and 125 ppm) was tested on the growth of five bacteria, Agrobacterium tumefaciens, Corynebacterium fascians, Erwinia carotovora, Pseudomonas solanacearum, and Streptomyces scabies and four fungi, Fusarium oxysporum f. sp. vasinfectum, Fusarium solani, Rhizoctonia solani, and Sclerotium bataticola.
