FENSULFOTHION

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H17O4PS2
Molecular Weight	308.354
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOP(=S)(OCC)OC1=CC=C(C=C1)[S+](C)[O-]

InChI

InChIKey=XDNBJTQLKCIJBV-UHFFFAOYSA-N

InChI=1S/C11H17O4PS2/c1-4-13-16(17,14-5-2)15-10-6-8-11(9-7-10)18(3)12/h6-9H,4-5H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C11H17O4PS2
Molecular Weight	308.354
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://pmep.cce.cornell.edu/profiles/insect-mite/fenitrothion-methylpara/fensulfothion/insect-prof-fensulfothion.html | http://www.inchem.org/documents/jmpr/jmpmono/v072pr17.htm

Fensulfothion is an organophosphate insecticide/nematicide. Fensulfothion is highly toxic to man and other non-target terrestrial and aquatic organisms from acute oral and dermal routes of exposure. Fensulfothion is registered for use as preplant or at-planting soil application to tobacco and various fruits and vegetables. Postplant topical applications are permitted in addition to the at-planting application on corn, peanuts, and rutabagas. Topical application is also permitted on commercial and ornamental turf. Fensulfothion is an organophosphate insecticide/nematicide that kills primarily by contact action, but also provides some systemic control of insects attacking the foliage of treated plants. The mode of action is by phosphorylating the acetylcholinesterase enzyme of tissues, allowing accumulation of acetylcholine at nerve junctions, with subsequent blocking effects upon the central nervous system.

CNS Activity

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Acetylcholinesterase 207 Target ID: CHEMBL220 Sources: http://pmep.cce.cornell.edu/profiles/insect-mite/fenitrothion-methylpara/fensulfothion/insect-prof-fensulfothion.html	Inhibitor 8297

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
High-performance liquid chromatographic separation of the enantiomers of organophosphorus pesticides on polysaccharide chiral stationary phases.	2001 Sep 14	11587332
Continuous flow microextraction combined with high-performance liquid chromatography for the analysis of pesticides in natural waters.	2006 Jul 28	16716335
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006 Nov	16497524
Longitudinal trends in organophosphate incidents reported to the National Pesticide Information Center, 1995-2007.	2009 Apr 20	19379510
Separation of organophosphorus pesticides by using nano-liquid chromatography.	2009 May 1	19321170
Livestock drugs and disease: the fatal combination behind breeding failure in endangered bearded vultures.	2010 Nov 30	21152405

Patents

Sample Use Guides

In Vivo Use Guide

Fensulfothion is used against soil nematodes (free living, root knot and cyst forming nematodes) and a broad spectrum of soil borne insects in field crops, vegetables and fruit. It is also used against nematodes in turf grasses, in flowers and in ornamentals. Fensulfothion is highly toxic to man and other non-target terrestrial and aquatic organisms from acute oral and dermal routes of exposure.

Route of Administration: Unknown

In Vitro Use Guide

The effect of fensulfothion at four concentrations (1, 5, 25, and 125 ppm) was tested on the growth of five bacteria, Agrobacterium tumefaciens, Corynebacterium fascians, Erwinia carotovora, Pseudomonas solanacearum, and Streptomyces scabies and four fungi, Fusarium oxysporum f. sp. vasinfectum, Fusarium solani, Rhizoctonia solani, and Sclerotium bataticola.

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:14:49 UTC 2023` Edited by `admin` on `Fri Dec 15 15:14:49 UTC 2023`
Record UNII	VB39B105PO
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FENSULFOTHION

Common Name

English

FENSULFOTHION [ISO]

Common Name

English

DMSP

Common Name

English

O,O-DIETHYL O-4-METHYLSULFINYLPHENYL PHOSPHOROTHIOATE

Common Name

English

1-(DIETHOXYTHIOXOPHOSPHINOOXY)-4-(METHYLSULFINYL)BENZENE

Systematic Name

English

BAY-25141

Common Name

English

PHOSPHOROTHIOIC ACID O,O-DIETHYL O-(4-(METHYLSULFINYL)PHENYL) ESTER

Systematic Name

English

SULFONIUM, (4-((DIETHOXYPHOSPHINOTHIOYL)OXY)PHENYL)HYDROXYMETHYL-, INNER SALT

Common Name

English

FENSULFOTHION [MI]

Common Name

English

O,O-DIETHYL O-(4-(METHYLSULFINYL)PHENYL) PHOSPHOROTHIOATE

Systematic Name

English

FENSULFOTHION [HSDB]

Common Name

English

BAY 25141

Common Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

32701