Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C22H24N2O8S |
| Molecular Weight | 476.5 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCOC1=C(OC)C=CC(=C1)[C@@H](CS(C)(=O)=O)N2C(=O)C3=CC=CC(NC(=O)CO)=C3C2=O
InChI
InChIKey=GAEOGEGXFOXKPH-MRXNPFEDSA-N
InChI=1S/C22H24N2O8S/c1-4-32-18-10-13(8-9-17(18)31-2)16(12-33(3,29)30)24-21(27)14-6-5-7-15(20(14)22(24)28)23-19(26)11-25/h5-10,16,25H,4,11-12H2,1-3H3,(H,23,26)/t16-/m1/s1
| Molecular Formula | C22H24N2O8S |
| Molecular Weight | 476.5 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 09:58:28 UTC 2023
by
admin
on
Sat Dec 16 09:58:28 UTC 2023
|
| Record UNII |
VAZ0AHM3I2
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
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VAZ0AHM3I2
Created by
admin on Sat Dec 16 09:58:28 UTC 2023 , Edited by admin on Sat Dec 16 09:58:28 UTC 2023
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PRIMARY | |||
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1384814-94-1
Created by
admin on Sat Dec 16 09:58:28 UTC 2023 , Edited by admin on Sat Dec 16 09:58:28 UTC 2023
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54764856
Created by
admin on Sat Dec 16 09:58:28 UTC 2023 , Edited by admin on Sat Dec 16 09:58:28 UTC 2023
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
PARENT -> METABOLITE |
Metabolites M7 and M17,which were present at trace levels in plasma, did retain some PDE4 and TNF-.alpha. inhibition activity, with IC 50 values similar to those of apremilast.
FECAL; URINE
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