THROMBOXANE B2

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H34O6
Molecular Weight	370.4804
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	2
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCC[C@H](O)\C=C\[C@@H](O)[C@@H](C\C=C/CCCC(O)=O)[C@@H](O)CC=O

InChI

InChIKey=FMNQRUKVXAQEAZ-JNRFBPFXSA-N

InChI=1S/C20H34O6/c1-2-3-6-9-16(22)12-13-18(23)17(19(24)14-15-21)10-7-4-5-8-11-20(25)26/h4,7,12-13,15-19,22-24H,2-3,5-6,8-11,14H2,1H3,(H,25,26)/b7-4-,13-12+/t16-,17+,18+,19-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C20H34O6
Molecular Weight	370.4804
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	2
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Experimental traumatic brain injury elevates brain prostaglandin E2 and thromboxane B2 levels in rats.	1988	3249309
High-performance liquid chromatographic assay of platelet-produced thromboxane B2.	1993 Jan 29	8454699
Relative contributions of direct and indirect mechanisms mediating endothelin-induced contraction of guinea-pig trachea.	1993 Nov	7507780
Wines and grape juices as modulators of platelet aggregation in healthy human subjects.	1996 Mar 15	8814965
Measurement of thromboxane B2 in platelet-rich human plasma by gas chromatography-mass spectrometry and gas chromatography-tandem mass spectrometry following extractive pentafluorobenzyl esterification.	1998 Jul 15	9683522
Plasma thromboxane B2 concentration in patients with ventricular septal defect and pulmonary hypertension.	1998 Mar	9583446
Comparison of in vitro-activity of commonly used topical glucocorticoids on cytokine- and phospholipase inhibition.	2004 Aug 31	15337628
Role of cyclooxygenase-2 in exacerbation of allergen-induced airway remodeling by multiwalled carbon nanotubes.	2013 Oct	23642096

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:47:24 GMT 2023` Edited by `admin` on `Sat Dec 16 08:47:24 GMT 2023`
Record UNII	V94M3R26ZV
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

THROMBOXANE B2

Common Name

English

THROMBOXANE B2 [MI]

Common Name

English

TXB2

Common Name

English

5-HEPTENOIC ACID, 7-((2R,3S,4S)-TETRAHYDRO-4,6-DIHYDROXY-2-((1E,3S)-3-HYDROXY-1-OCTEN-1-YL)-2H-PYRAN-3-YL)-, (5Z)-

Systematic Name

English

(5Z,9.ALPHA.,13E,15S)-9,11,15-TRIHYDROXYTHROMBOXA-5,13-DIEN-1-OIC ACID

Systematic Name

English

PHD

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C879