TUNGSTEN

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	W
Molecular Weight	183.84
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[W]

InChI

InChIKey=WFKWXMTUELFFGS-UHFFFAOYSA-N

InChI=1S/W

HIDE SMILES / InChI

Molecular Formula	W
Molecular Weight	183.84
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Hypoxia injures endothelial cells by increasing endogenous xanthine oxidase activity.	1992 Apr 15	1314387
Dehydrogenase conversion to oxidase and lipid peroxidation in brain after carbon monoxide poisoning.	1992 Oct	1447108
Podocyte architecture in puromycin aminonucleoside-treated rats administered tungsten or allopurinol.	1995 Sep-Oct	7583048
Effect of the militarily-relevant heavy metals, depleted uranium and heavy metal tungsten-alloy on gene expression in human liver carcinoma cells (HepG2).	2004 Jan	14971665
Metals in urine and peripheral arterial disease.	2005 Feb	15687053
Embedded weapons-grade tungsten alloy shrapnel rapidly induces metastatic high-grade rhabdomyosarcomas in F344 rats.	2005 Jun	15929896
Oral administration of sodium tungstate improves cardiac performance in streptozotocin-induced diabetic rats.	2005 May	15897922
Xanthine oxidase inhibitor tungsten prevents the development of atherosclerosis in ApoE knockout mice fed a Western-type diet.	2006 Nov 1	17023262
Reactive oxygen species and oxidative DNA damage mediate the cytotoxicity of tungsten-nickel-cobalt alloys in vitro.	2011 Jan 1	20934443
Pulmonary toxicity after exposure to military-relevant heavy metal tungsten alloy particles.	2012 Feb 15	22198552
In vivo corrosion, tumor outcome, and microarray gene expression for two types of muscle-implanted tungsten alloys.	2012 Nov 15	22982072
Genotoxic changes to rodent cells exposed in vitro to tungsten, nickel, cobalt and iron.	2014 Mar 10	24619124
Tungsten targets the tumor microenvironment to enhance breast cancer metastasis.	2015 Jan	25324207
Molecular basis of carcinogenicity of tungsten alloy particles.	2015 Mar 15	25620057

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:43:28 UTC 2023` Edited by `admin` on `Fri Dec 15 19:43:28 UTC 2023`
Record UNII	V9306CXO6G
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TUNGSTEN

Systematic Name

English

TUNGSTEN [HSDB]

Common Name

English

Tungsten [WHO-DD]

Common Name

English

TUNGSTEN [MI]

Common Name

English

Classification Tree Code System Code

DSLD

3354 (Number of products:25)