THIOCTATE TROMETAMOL

Details

Stereochemistry	RACEMIC
Molecular Formula	C8H14O2S2.C4H11NO3
Molecular Weight	327.461
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(CO)(CO)CO.OC(=O)CCCCC1CCSS1

InChI

InChIKey=CCTREOMTIFSZAU-UHFFFAOYSA-N

InChI=1S/C8H14O2S2.C4H11NO3/c9-8(10)4-2-1-3-7-5-6-11-12-7;5-4(1-6,2-7)3-8/h7H,1-6H2,(H,9,10);6-8H,1-3,5H2

HIDE SMILES / InChI

Molecular Formula	C4H11NO3
Molecular Weight	121.135
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C8H14O2S2
Molecular Weight	206.326
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.rxwiki.com/trometamol | http://www.tabletwise.com/medicine/trometamol | https://pubchem.ncbi.nlm.nih.gov/compound/tromethamine

Trometamol is an organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Acidosis 1 Sources: https://www.rxwiki.com/trometamol http://www.tabletwise.com/medicine/trometamol	Primary		Approved 8429	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
The treatment of acidosis in acute lung injury with tris-hydroxymethyl aminomethane (THAM).	2000 Apr	10764304
Sodium bicarbonate versus THAM in ICU patients with mild metabolic acidosis.	2005 May-Jun	16013019

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:31:39 GMT 2023` Edited by `admin` on `Sat Dec 16 08:31:39 GMT 2023`
Record UNII	V8276EBZ06
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

THIOCTATE TROMETAMOL

Common Name

English

1,2-DITHIOLANE-3-PENTANOIC ACID, COMPD. WITH 2-AMINO-2-(HYDROXYMETHYL)-1,3-PROPANEDIOL (1:1)

Systematic Name

English

Thioctate trometamol [WHO-DD]

Common Name

English

1,3-PROPANEDIOL, 2-AMINO-2-(HYDROXYMETHYL)-, 1,2-DITHIOLANE-3-PENTANOATE (SALT)

Common Name

English

1,3-PROPANEDIOL, 2-AMINO-2-(HYDROXYMETHYL)-, 1,2-DITHIOLANE-3-VALERATE (SALT)

Common Name

English

1,2-DITHIOLANE-3-VALERIC ACID, COMPD. WITH 2-AMINO-2-(HYDROXYMETHYL)-1,3-PROPANEDIOL (1:1)

Common Name

English

Code System Code Type Description

ECHA (EC/EINECS)

238-329-9