OBEVERSEN SODIUM

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 16:32:14 GMT 2023` Edited by `admin` on `Sat Dec 16 16:32:14 GMT 2023`
Nucleic Acid Type	OLIGONUCLEOTIDE
Nucleic Acid Subtype	ANTI-SENSE
Sequence Type	COMPLETE
Record UNII	V7THR3L5GC
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

OBEVERSEN SODIUM

Official Name

English

ION-769357

Code

English

DNA, D((2'-O-(2-METHOXYETHYL))M5RU-SP-(2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))RA-T-SP-T-SP-T-SP-A-SP-A-SP-T-SP-G-SP-A-SP-G-SP-M5C-SP-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))M5RU-

Common Name

English

OBEVERSEN SODIUM [USAN]

Common Name

English

Code System Code Type Description

USAN

HI-40

Created by admin on Sat Dec 16 16:32:14 GMT 2023 , Edited by admin on Sat Dec 16 16:32:14 GMT 2023

PRIMARY

CAS

2304711-35-9

Created by admin on Sat Dec 16 16:32:14 GMT 2023 , Edited by admin on Sat Dec 16 16:32:14 GMT 2023

PRIMARY

NCI_THESAURUS

C186414

Created by admin on Sat Dec 16 16:32:14 GMT 2023 , Edited by admin on Sat Dec 16 16:32:14 GMT 2023

PRIMARY

FDA UNII

V7THR3L5GC

Created by admin on Sat Dec 16 16:32:14 GMT 2023 , Edited by admin on Sat Dec 16 16:32:14 GMT 2023

PRIMARY

Sugar	Site Range	Site Count
Deoxyribose (DNA)	1_6-1_15	10 / 20
2'-O-Methoxyethyl ribose	1_1-1_5;1_16-1_20	10 / 20

Linkage	Site Range	Site Count
	1_3-1_6;1_17-1_18	6 / 19
Sodium Phosporothioate	1_2;1_7-1_16;1_19-1_20	13 / 19

Related Record Type Details


					BX8TS73ATE

OBEVERSEN

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Extent	Fragment Name	Fragment Approval
NUCLEOTIDE SUBSTITUTION	[1_1]	5'-TERMINUS		UNSPECIFIED SUBSTANCE	3a98b2f0 (not in database)
NUCLEOSIDE BASE SUBSTITUTION	[1_1] [1_16] [1_17]	SITE_SPECIFIC	Amount:	THYMINE	QR26YLT7LT
NUCLEOSIDE BASE SUBSTITUTION	[1_3] [1_4] [1_15] [1_18] [1_20]	SITE_SPECIFIC		5-METHYLCYTOSINE	6R795CQT4H