Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C19H17N3O2S2 |
| Molecular Weight | 383.487 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O=S(=O)(NC1=CC=CC=C1)C2=CC=C(NC(=S)NC3=CC=CC=C3)C=C2
InChI
InChIKey=HNDRSTUKPCLQLT-UHFFFAOYSA-N
InChI=1S/C19H17N3O2S2/c23-26(24,22-17-9-5-2-6-10-17)18-13-11-16(12-14-18)21-19(25)20-15-7-3-1-4-8-15/h1-14,22H,(H2,20,21,25)
| Molecular Formula | C19H17N3O2S2 |
| Molecular Weight | 383.487 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| QseC Signaling in the Outbreak O104:H4 Escherichia coli Strain Combines Multiple Factors during Infection. | 2019-09-01 |
|
| LED 209 conjugated chitosan as a selective antimicrobial and potential anti-adhesion material. | 2019-02-15 |
|
| Indole-Induced Reversion of Intrinsic Multiantibiotic Resistance in Lysobacter enzymogenes. | 2017-09-01 |
|
| Pyroptosis of Salmonella Typhimurium-infected macrophages was suppressed and elimination of intracellular bacteria from macrophages was promoted by blocking QseC. | 2016-11-17 |
|
| Adrenergic antagonists restrict replication of Legionella. | 2015-07 |
|
| A potent and selective antimicrobial poly(amidoamine) dendrimer conjugate with LED209 targeting QseC receptor to inhibit the virulence genes of gram negative bacteria. | 2015-02 |
|
| QseC inhibitors as an antivirulence approach for Gram-negative pathogens. | 2014-11-11 |
|
| Norepinephrine and dopamine increase motility, biofilm formation, and virulence of Vibrio harveyi. | 2014 |
|
| Genome-wide transposon mutagenesis identifies a role for host neuroendocrine stress hormones in regulating the expression of virulence genes in Salmonella. | 2010-02 |
|
| Disarming, not destroying: targeting QseC. | 2008-10 |
|
| Targeting QseC signaling and virulence for antibiotic development. | 2008-08-22 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 23:27:04 GMT 2025
by
admin
on
Mon Mar 31 23:27:04 GMT 2025
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| Record UNII |
V62AG9LR2G
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| Record Status |
Validated (UNII)
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| Record Version |
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245342-14-7
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V62AG9LR2G
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3421033
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