U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry UNKNOWN
Molecular Formula C17H22N2O2
Molecular Weight 286.3688
Optical Activity ( + )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FENPIPALONE, (+)-

SMILES

CN1CC(CCN2CCC(=CC2)C3=CC=CC=C3)OC1=O

InChI

InChIKey=YUORBURTMIUPMW-UHFFFAOYSA-N
InChI=1S/C17H22N2O2/c1-18-13-16(21-17(18)20)9-12-19-10-7-15(8-11-19)14-5-3-2-4-6-14/h2-7,16H,8-13H2,1H3

HIDE SMILES / InChI

Molecular Formula C17H22N2O2
Molecular Weight 286.3688
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

FENPIPALONE is an oxazolidinone derivative with central nervous system depressant and antiinflammatory activity in animal models. However, FENPIPALONE did not demonstrate any usefulness for severely ill chronic schizophrenic patients.

CNS Activity

Curator's Comment: Known to be CNS active in mouse and probably not active in human.

Approval Year

PubMed

PubMed

TitleDatePubMed
5-(2-Aminoethyl)-2-oxazolidinones with central nervous system depressant and antiinflammatory activity.
1973-10
Two pilot studies of AHR-1680 in chronic schizophrenic patients.
1969-05-01
Substance Class Chemical
Created
by admin
on Mon Mar 31 23:39:39 GMT 2025
Edited
by admin
on Mon Mar 31 23:39:39 GMT 2025
Record UNII
V5KT8AA96K
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
2-OXAZOLIDINONE, 5-(2-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)ETHYL)-3-METHYL-, (+)-
Preferred Name English
FENPIPALONE, (+)-
Common Name English
Code System Code Type Description
CAS
55121-37-4
Created by admin on Mon Mar 31 23:39:39 GMT 2025 , Edited by admin on Mon Mar 31 23:39:39 GMT 2025
PRIMARY
FDA UNII
V5KT8AA96K
Created by admin on Mon Mar 31 23:39:39 GMT 2025 , Edited by admin on Mon Mar 31 23:39:39 GMT 2025
PRIMARY
Related Record Type Details
ENANTIOMER -> ENANTIOMER