| Stereochemistry | ABSOLUTE |
| Molecular Formula | C7H15N5O4 |
| Molecular Weight | 233.2251 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC(=O)[C@@H](N)CCCNC(=N)N[N+]([O-])=O
InChI
InChIKey=KCWZGJVSDFYRIX-YFKPBYRVSA-N
InChI=1S/C7H15N5O4/c1-16-6(13)5(8)3-2-4-10-7(9)11-12(14)15/h5H,2-4,8H2,1H3,(H3,9,10,11)/t5-/m0/s1
| Molecular Formula | C7H15N5O4 |
| Molecular Weight | 233.2251 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
| 39.0 nM [Ki] | |||
| 4.44 null [pIC50] |
PubMed
Patents
Sample Use Guides
Rats: Nitroarginine inhibits NO synthase activity in the brain after i.p. administration of 5 or 50 mg/kg.
Route of Administration:
Intraperitoneal
The vasodilator responses evoked by low doses of 5-HT (5 x 10(-10)-10(-8) mol) were almost abolished by Nitroarginine (L-NOARG) (at 10(-4) M). The vasodilator response evoked by substance P (5 x 10(-12)-5 x 10(-9) mol) was reduced in the presence of L-NOARG ( 3 x 10(-5) M). The response to substance P was almost abolished by L-NOARG (at 10(-4) M).
