CX3C chemokine receptor 1

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 17:36:26 GMT 2025` Edited by `admin` on `Tue Apr 01 17:36:26 GMT 2025`
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	V4T51BN6OQ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Beta chemokine receptor-like 1

Preferred Name

English

CX3C chemokine receptor 1

Common Name

English

CMK-BRL-1

Common Name

English

FRACTALKINE RECECPTOR

Common Name

English

GPR13

Common Name

English

G-protein coupled receptor 13

Common Name

English

CMKBRL1

Common Name

English

V28

Common Name

English

Code System Code Type Description

UNIPROT

P49238

Created by admin on Tue Apr 01 17:36:26 GMT 2025 , Edited by admin on Tue Apr 01 17:36:26 GMT 2025

PRIMARY

FDA UNII

V4T51BN6OQ

Created by admin on Tue Apr 01 17:36:26 GMT 2025 , Edited by admin on Tue Apr 01 17:36:26 GMT 2025

PRIMARY

From	To
1_102	1_175

Related Record Type Details


					S9Y83SS7PQ

Rugocrixan

NEGATIVE ALLOSTERIC MODULATOR (NAM)->TARGET

Comments:

non-competitive allosteric modulator of CX3CL1, binding CX3CR1 and effecting G-protein signalling and ?-arrestin recruitment in a biased way.

Interaction Type:

ALLOSTERIC

Qualification:

Kd

Amount:


					4ZXD25SC4S

Fosrugocrixan

INHIBITOR -> TARGET

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_346]				THREONINE PHOSPHATE	3L4WX7B1EI

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL
Molecular Formula	CHEMICAL