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Details

Stereochemistry ABSOLUTE
Molecular Formula C22H23N3O6S
Molecular Weight 457.5
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ETAVOPIVAT

SMILES

OC[C@@H](C(=O)N1CC2=C(C1)CN(C2)S(=O)(=O)C3=CN=C4OCCOC4=C3)C5=CC=CC=C5

InChI

InChIKey=KZFFYEPYCVDOGE-LJQANCHMSA-N
InChI=1S/C22H23N3O6S/c26-14-19(15-4-2-1-3-5-15)22(27)24-10-16-12-25(13-17(16)11-24)32(28,29)18-8-20-21(23-9-18)31-7-6-30-20/h1-5,8-9,19,26H,6-7,10-14H2/t19-/m1/s1

HIDE SMILES / InChI

Molecular Formula C22H23N3O6S
Molecular Weight 457.5
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Substance Class Chemical
Created
by admin
on Thu Jul 06 20:47:36 UTC 2023
Edited
by admin
on Thu Jul 06 20:47:36 UTC 2023
Record UNII
V4E0A9M44Q
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ETAVOPIVAT
USAN   INN  
Official Name English
ETAVOPIVAT [USAN]
Common Name English
(S)-1-(5-((2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-7-yl)sulfonyl)-3,4,5,6-tetrahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)-3-hydroxy-2-phenylpropan-1-one
Systematic Name English
etavopivat [INN]
Common Name English
FT-4202
Code English
1-Propanone, 1-[5-[(2,3-dihydro-1,4-dioxino[2,3-b]pyridin-7-yl)sulfonyl]-3,4,5,6-tetrahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-3-hydroxy-2-phenyl-, (2S)-
Systematic Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 728919
Created by admin on Thu Jul 06 20:47:36 UTC 2023 , Edited by admin on Thu Jul 06 20:47:36 UTC 2023
Code System Code Type Description
PUBCHEM
135338378
Created by admin on Thu Jul 06 20:47:36 UTC 2023 , Edited by admin on Thu Jul 06 20:47:36 UTC 2023
PRIMARY
INN
11646
Created by admin on Thu Jul 06 20:47:36 UTC 2023 , Edited by admin on Thu Jul 06 20:47:36 UTC 2023
PRIMARY INN
SMS_ID
300000016921
Created by admin on Thu Jul 06 20:47:36 UTC 2023 , Edited by admin on Thu Jul 06 20:47:36 UTC 2023
PRIMARY
FDA UNII
V4E0A9M44Q
Created by admin on Thu Jul 06 20:47:36 UTC 2023 , Edited by admin on Thu Jul 06 20:47:36 UTC 2023
PRIMARY
NCI_THESAURUS
C176893
Created by admin on Thu Jul 06 20:47:36 UTC 2023 , Edited by admin on Thu Jul 06 20:47:36 UTC 2023
PRIMARY
CAS
2245053-57-8
Created by admin on Thu Jul 06 20:47:36 UTC 2023 , Edited by admin on Thu Jul 06 20:47:36 UTC 2023
PRIMARY
USAN
KL-51
Created by admin on Thu Jul 06 20:47:36 UTC 2023 , Edited by admin on Thu Jul 06 20:47:36 UTC 2023
PRIMARY
Related Record Type Details
TARGET -> ACTIVATOR
activator to 89% of activity
EC50
Related Record Type Details
ACTIVE MOIETY