Details
Stereochemistry | ACHIRAL |
Molecular Formula | C21H34N2O.ClH |
Molecular Weight | 366.968 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CCCCCCN1CCC(CC1)(C(=O)N(C)CC)C2=CC=CC=C2
InChI
InChIKey=VFXXNIHMKMOIQN-UHFFFAOYSA-N
InChI=1S/C21H34N2O.ClH/c1-4-6-7-11-16-23-17-14-21(15-18-23,20(24)22(3)5-2)19-12-9-8-10-13-19;/h8-10,12-13H,4-7,11,14-18H2,1-3H3;1H
Molecular Formula | ClH |
Molecular Weight | 36.461 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | C21H34N2O |
Molecular Weight | 330.5075 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Sameridine was developed as a compound with both local anesthetic and opioid properties (partial micro-opioid receptor agonist). This drug participated in clinical trials when administered intrathecally to provide anesthesia for surgery and extended postoperative analgesia. However, further development of this drug was discontinued.
Originator
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/12538214
Twenty-four healthy volunteers received either 25 mg of sameridine or 15 mg of bupivacaine intrathecally. Ventilation was measured by pneumotachography and in-line capnography
Route of Administration:
Other
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 14:47:09 GMT 2023
by
admin
on
Sat Dec 16 14:47:09 GMT 2023
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Record UNII |
V3TSQ43P49
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Record Status |
Validated (UNII)
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Record Version |
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9842135
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136483-84-6
Created by
admin on Sat Dec 16 14:47:09 GMT 2023 , Edited by admin on Sat Dec 16 14:47:09 GMT 2023
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PARENT -> SALT/SOLVATE |
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ACTIVE MOIETY |
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