DIPHENYL SULFONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H10O2S
Molecular Weight	218.272
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=S(=O)(C1=CC=CC=C1)C2=CC=CC=C2

InChI

InChIKey=KZTYYGOKRVBIMI-UHFFFAOYSA-N

InChI=1S/C12H10O2S/c13-15(14,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H

HIDE SMILES / InChI

Molecular Formula	C12H10O2S
Molecular Weight	218.272
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Diarylsulfones, a new chemical class of nonnucleoside antiviral inhibitors of human immunodeficiency virus type 1 reverse transcriptase.	1993 Apr	7684215
Resistance to 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives is generated by mutations at multiple sites in the HIV-1 reverse transcriptase.	1995 Jun 20	7540784
Characteristics of a group of nonnucleoside reverse transcriptase inhibitors with structural diversity and potent anti-human immunodeficiency virus activity.	1995 Oct	7475321
Biological and biochemical anti-human immunodeficiency virus activity of UC 38, a new non-nucleoside reverse transcriptase inhibitor.	1996 Jan	8558446
Highly potent oxathiin carboxanilide derivatives with efficacy against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus isolates.	1997 Apr	9087499
Unique anti-human immunodeficiency virus activities of the nonnucleoside reverse transcriptase inhibitors calanolide A, costatolide, and dihydrocostatolide.	1999 Aug	10428899
A simple enantioselective synthesis of serratenediol.	2001 Oct 4	11574034
HPLC analysis of 4-chlorophenyl methyl sulphide and diphenyl sulphide and their corresponding sulphoxides and sulphones in rat liver microsomes.	2002 Jan 1	11682239
[A case of Hansen's disease seen in an Indonesian resident, and tracing of the patient after coming back to Indonesia].	2003 Aug	14598635
Antifungal activity of organobismuth compounds against the yeast Saccharomyces cerevisiae: structure-activity relationship.	2004 Mar	14987856
Cytotoxic chromenes from Myriactis humilis.	2005 Apr	15856418
Determination of the sulphoxides and sulphones of three simple sulphides in rat urine: effects of phenobarbitone, beta-naphthoflavone and methimazole.	2005 Jan	15470701
Polysulfone-ZrO(2) surface interactions. The influence on formation, morphology and properties of zirfon-membranes.	2006 Apr 13	16599520
Chlorodifluoromethyl phenyl sulfone: a novel non-ozone-depleting substance-based difluorocarbene reagent for O- and N-difluoromethylations.	2007 Dec 28	18060124
Bis[4-(2-hydroxy-ethyl-amino)phen-yl] sulfone.	2007 Dec 6	21200738
5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part III: molecular modeling studies on binding contribution of 1-(5-methylsulfonyl)pyrid-2-yl and 4-nitrile.	2007 Feb 15	17126015
A reductive cyclization approach to attenol A.	2007 Mar 30	17346087
Stereoselective synthesis of a C-linked neuraminic acid disaccharide: potential building block for the synthesis of C-analogues of polysialic acids.	2008 Dec 5	19006371
Bis(3-nitro-phen-yl) sulfone.	2008 Jul 5	21203099
Hydride affinities of cumulated, isolated, and conjugated dienes in acetonitrile.	2008 Nov 7	18821805
3,5-Difluoro-phenyl phenyl sulfone.	2008 Oct 25	21581065
Application of passive sampling devices for screening of micro-pollutants in marine aquaculture using LC-MS/MS.	2009 Feb 15	19084673
4-Chloro-N-(4-chloro-phenyl-sulfon-yl)-N-(3-oxo-2,3-dihydro-1,2-benzisothia-zol-2-yl)benzene-sulfonamide.	2009 Jan 31	21582006
Synthesis, characterization and antibacterial activity of some triazole Mannich bases carrying diphenylsulfone moieties.	2009 Jul	18708273
Polystyrene bound oxidovanadium(IV) and dioxidovanadium(V) complexes of histamine derived ligand for the oxidation of methyl phenyl sulfide, diphenyl sulfide and benzoin.	2009 Mar 28	19274297
Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties.	2009 Nov	19616347
Benzhydryl phenyl sulfone.	2009 Nov 28	21578931
Identification of phenylsulfone-substituted quinoxaline (WYE-672) as a tissue selective liver X-receptor (LXR) agonist.	2010 Apr 22	20350005
Synthesis and antimicrobial evaluation of some fused heterocyclic [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives.	2010 Dec	21036422
Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides: part II.	2010 Jan 1	19932972
Environmental and human health risk assessment of organic micro-pollutants occurring in a Spanish marine fish farm.	2010 May	19932535

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:46:13 UTC 2023` Edited by `admin` on `Fri Dec 15 18:46:13 UTC 2023`
Record UNII	V25W2CFS3M
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIPHENYL SULFONE

Systematic Name

English

DIPHENYL SULFONE [MI]

Common Name

English

1,1'-SULFONYLBISBENZENE

Systematic Name

English

PHENYL SULFONE

Systematic Name

English

SULFOBENZIDE

Common Name

English

DIPHENYLSULFONE

Systematic Name

English

NSC-6780

Code

English

NSC-627706

Code

English

DIPHENYL SULPHONE

Systematic Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

399500